Oddly, 6MP never affected me with fatigue. My white count has me a bit concerned, being only 2.9 but then it is somewhat better than three months ago when it was 2.4. I try to stay away from people who are sick. Being retired that isn't much of a problem for me.
I am surprised that your doctor didn't have you take the 6MP along with the prednisone. My GI doctor started me on the 6MP over five years ago while I was taking prednisone. It took about three months to "kick in". Last year he took me off the 6MP for a short while because my pancreatic enzyme levels were extremely high when I was admitted to the hospital in the beginning of May. At my follow up visit to his office he put me back on the 6MP because my enzyme levels had returned to normal. I have them checked every three months and they are still well within normal limits. So, I have no idea why they were so out of whack. Wonder if the lab didn't make a mistake.
I noticed my hair is thinning out quite a bit, but then again I am getting older too. If it is due to the 6MP it's a small price to pay for remission. I'll take thin hair over a flare of UC any day.
62 yr old granny. South Jersey
Diagnosed with ulcerative proctitis in 1998 in hospital
Hospitalized (2nd time) in May 2008
Update 11/03/08...finally in remission!! Hope I don't jinx myself. Off the prednisone since 11/01/08...now see if I can stay off for longer than two weeks. Other meds: 6MP (75 mgm), colazal (6 per day), Benicar and Toprol (high blood pressure meds), Probiotic (2 per day), fish oil capsule and multi-vitamin and calcium with vitamin D.