Question - Is this a symptom of Remicade or not?

New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

MRey
New Member


Date Joined Mar 2009
Total Posts : 3
   Posted 3/23/2009 8:03 PM (GMT -6)   
Hello,
I just joined the forum today as I thought I would reach out to others with UC to see if they are experiencing the same symptoms as I am.
 
I started Remicade in November 06, and by January my UC was under control.  :-)
confused   However I am now experiencing joint pain & swelling that travels from one joint to another.  It seems to start two weeks after my infusions and lasts 1-2 weeks.  I have had blood work and x-rays done and no abnormalities have been found (thankfully).  I don't know if this is related to the remicade or not or maybe even the UC; has anyone else experienced similar joint pain? 
 
 
 
 

jujub
Elite Member


Date Joined Mar 2003
Total Posts : 10407
   Posted 3/23/2009 8:13 PM (GMT -6)   
Arthritis is one of the common extra-intestinal effects of UC. In my case, the joint pain came before the GI symptoms! So it could very well be that. I don't know if it's also a possible side effect from Remi. I've been on it for three years with no problems.

My arthritis has affected my hips, knees elbows, ankles, wrists and hands, as well as the sacro-iliac joint in my back. It's better since I've been on treatment for the UC, but has been quite bad at times. If you have too much problem, you may want to see a rheumatologist.

Welcome to HealingWell.
Judy
 
Moderate to severe left-sided UC (21 cm) diagnosed 2001.
Avascular necrosis in both shoulders is my "forever" gift from Entocort.
Colazal,  Remicade, Nature's Way Primadophilus Reuteri. In remission since April, 2006.
"My life is an ongoing medical adventure"
 
Co-Moderator UC Forum
Please remember to consult your health care provider when making health-related decisions.


MRey
New Member


Date Joined Mar 2009
Total Posts : 3
   Posted 3/23/2009 8:22 PM (GMT -6)   
Thanks for the quick response. I have read that Arthritis is common in those who have UC. Since my joint pain started after I started taking Remicade, I was a bit nervous that it may be a side effect. The pain and swelling can get pretty bad at times, and then other times I don't have any discomfort. Knowing that it is more likely linked to the UC makes me feel better. Thanks!

Julia Hill
Veteran Member


Date Joined Mar 2008
Total Posts : 562
   Posted 3/23/2009 8:37 PM (GMT -6)   

Hi,

Sorry to hear about your joint pain.  I too experienced this with remicade.  The joint pain became worse after each infusion, and I was diagnosed by a Rheumy with Remicade induced Lupus.  You need to have bloodwork done for a positive ANA etc..  It will not show up on an x-ray.  All the best to you, and keep us posted.

Julia

 


Probiotic
Veteran Member


Date Joined Mar 2007
Total Posts : 2832
   Posted 3/23/2009 9:47 PM (GMT -6)   
You must be reading my mind because I have been getting joint pains too since being on remicade.  They are on and off and mostly mild.  My blood tests have been normal, and my CRP and SED inflammation markers have been low too.  Is the blood test for ANA a special one- i.e. this wouldn't show up in a CBC etc?  I am on the verge of being increased to double dose Remicade because the Remi seems to become inefefctive after a fdw weeks... but the mild joint pains are giving me the creeps a bit.  On the flip side, it has allowed me to get down to very low levels of prednisone (not yet off though without flaring) and hence get rid of the different types of joint pains - mostly joint stiffness- that i got from pred.  I'll say this much- when I tried Imuran I got some of these joint aches too, and they disappeared when I stopped the drug.  Right now my priority is to get into a full remission, and also to buy time to try some last ditch non-drug approaches such as fecal infusions. 



Pancolitis >20 years, allergic to all 5ASAs
Tried everything under the sun (natural and alternative)
Some partial success with TSO but was too expensive to keep up 
Currently Remicade and lots of probiotics, tapering pred again, maybe surgery this year
 
 

Post Edited (Probiotic) : 3/23/2009 8:50:49 PM (GMT-6)


bookworm21
Veteran Member


Date Joined Mar 2008
Total Posts : 1766
   Posted 3/23/2009 10:01 PM (GMT -6)   
I hadn't had joint pain until February, and I started Remicade last June. My theory is that it's a side effect from Remicade since I had never had joint pain before and I'm otherwise in remission. Yes, I'm pretty sure the ANA test does not show up on the CBC. I just had my blood drawn today, and they were able to tell me my CBC results a few hours later and I won't get my ANA results until later this week. If it comes back positive, then my GI will take me off of Remicade.
 
Julia, do you still have symptoms? Did the lupus go away once you stopped Remicade?
Female, Age 20
9 Asacol, Rowasa1000 mg Canasa, Proctofoam, Rifaximin 2/day
Digestive Advantage (Crohn's & Colitis)1 Florastor, 50 mg 6MP,1 Primadophilus reuteri, Remicade (6 infusions), 2.4 g Lialda, Forvia, 6 Colazal, 1 Anucort, Culturelle, Fish Oil, Calcium/Vit D supplement, 20 mg Prozac, VSL #3 DS, Turmeric
 


Probiotic
Veteran Member


Date Joined Mar 2007
Total Posts : 2832
   Posted 3/24/2009 11:36 AM (GMT -6)   
MRey said...
Hello,
I just joined the forum today as I thought I would reach out to others with UC to see if they are experiencing the same symptoms as I am.
 
I started Remicade in November 06, and by January my UC was under control.  :-)
confused   However I am now experiencing joint pain & swelling that travels from one joint to another.  It seems to start two weeks after my infusions and lasts 1-2 weeks.  I have had blood work and x-rays done and no abnormalities have been found (thankfully).  I don't know if this is related to the remicade or not or maybe even the UC; has anyone else experienced similar joint pain? 
 
 
 
 
I found this post on another forum (I hope it is ok to post the link here) which describes symptoms exactly what I am experiencing and perhaps exactly what you are too.... I am going to get an ANA test asap.  I always seem to have astoundingly normal blood test results so we'll see, but I am feeling certain the Remi, while doing good things for the UC, is also causing these pains and may potentially have to be discontinued.  The good news - if the Remi is the cause- is that this sort of stuff does normally disappear as the drug dissipates, but the bad news is I am down to my last shots here to save my colon.  Here is the link to a post on a Crohn's site....
 
 

Pancolitis >20 years, allergic to all 5ASAs
Tried everything under the sun (natural and alternative)
Some partial success with TSO but was too expensive to keep up 
Currently Remicade and lots of probiotics, tapering pred again, maybe surgery this year
 
 


MRey
New Member


Date Joined Mar 2009
Total Posts : 3
   Posted 3/24/2009 7:19 PM (GMT -6)   
Hey,
 
Well it sounds like others are experiencing the same pains as I am.  Honestly today I am feeling fine, but the last few days my left knee and right hand joints were real bad. 
I worry that the Remicade is the cause; scared about having to stop the drug and also scared of the unknown if I remain on the drug. I've also been told that it is my last chance at saving my colon; in 06 I had to decide between taking Remicade or having the surgery.  At this time I'm thankful that Remicade has my UC under control, but I worry that the joint pain could be the sign of another potentially bigger problem. 
 
Probiotic - thanks for posting the link, it sounds similar...
 
I will be seeing my doctor next week & hopefully I can get some answers.  It helps to talk to others and know I'm not alone.
 

Julia Hill
Veteran Member


Date Joined Mar 2008
Total Posts : 562
   Posted 3/24/2009 9:17 PM (GMT -6)   
Hi Bookworm21,

An ANA bloodtest is seperate from a CBC. The joint pain did improve after discontinuing the remicade, but I did need to take prednisone and MTX. I have never experienced joint pain like that in the 29 years I've had crohn's, and I hope I never do again. According to my bloodwork, it took 1.5 years before it came back negative (special testing was done by rheumy every 6 months).

All the best to you,

Julia

vega19
Regular Member


Date Joined Sep 2008
Total Posts : 91
   Posted 3/24/2009 10:55 PM (GMT -6)   

I started getting joint pain for the first time about a month ago. It was starting to fade until I had my last Remicade infusion about 2 weeks ago. Then it became more frequent and painful. It's finally starting to fade again. I'll have to bring up this ANA test when I see my GI in a few weeks.


31 year old female diagnosed with UC (entire colon) Feb 2008
(4) 400mg Asacol 3x a day
Remicade 10mg/kg every 8 weeks
Omega 3 supp, calcium supp
probiotic


bookworm21
Veteran Member


Date Joined Mar 2008
Total Posts : 1766
   Posted 3/25/2009 8:20 AM (GMT -6)   
My joint pains aren't too bad, but it depends on the day. Right after my infusion on Monday, I started getting sharp pains in my left wrist. And my wrists have been hurting a little worse over the last couple of days, but my knees are completely fine. I seem to have other possible symptoms of lupus as well--hair loss, weight loss, fatigue, bruising, and of course joint/muscle pain.

I hope I get my ANA results today; I can't wait any longer!
Female, Age 20
9 Asacol, Rowasa1000 mg Canasa, Proctofoam, Rifaximin 2/day
Digestive Advantage (Crohn's & Colitis)1 Florastor, 50 mg 6MP,1 Primadophilus reuteri, Remicade (6 infusions), 2.4 g Lialda, Forvia, 6 Colazal, 1 Anucort, Culturelle, Fish Oil, Calcium/Vit D supplement, 20 mg Prozac, VSL #3 DS, Turmeric
 


bookworm21
Veteran Member


Date Joined Mar 2008
Total Posts : 1766
   Posted 3/27/2009 4:45 PM (GMT -6)   
How's everyone's joint pain?

My ANA test came back negative, so I still don't know what the joint pain is from. My PCP ordered a double-stranded DNA test, which is more specific than the ANA. She said she was really worried about the joint pain, and regardless of the blood test results, I should see a rheumatologist.
Female, Age 20
9 Asacol, Rowasa1000 mg Canasa, Proctofoam, Rifaximin 2/day
Digestive Advantage (Crohn's & Colitis)1 Florastor, 50 mg 6MP,1 Primadophilus reuteri, Remicade (7 infusions), 2.4 g Lialda, Forvia, 6 Colazal, 1 Anucort, Culturelle, Fish Oil, Calcium/Vit D supplement, 20 mg Prozac, VSL #3 DS, Turmeric
 


Probiotic
Veteran Member


Date Joined Mar 2007
Total Posts : 2832
   Posted 3/30/2009 11:01 PM (GMT -6)   
My joint pain has gone about 90% away now. It was certainly not disabling but was obnoxious. I like to work out in the gym regularly and it made doing my normal routine difficult as the joints were so sensitized. I just had an ANA test done and should know the results later this week, but I wonder if abnormalities would only show up at the time the pains were stronger?
Pancolitis >20 years, allergic to all 5ASAs
Tried everything under the sun (natural and alternative)
Some partial success with TSO but was too expensive to keep up 
Currently Remicade and lots of probiotics, tapering pred again, maybe surgery this year
 
 


JLG45
Regular Member


Date Joined Feb 2009
Total Posts : 114
   Posted 3/30/2009 11:41 PM (GMT -6)   
After my 2nd Remi treatment I did have swelling below the knees for about 1 week. Benedryl seemed to solve the problem.

Just finished my 3d treatment yesterday. The GI suggested I take Benedryl for about 5 days.

No joint pain but I do have muscle cramps in my calves. Could be because of the Prednisone.
Diagnosed U.Proctitis 07

Flare Feb 09 - Diagnosed with Severe Pancolitis
Remicade, 50mg Prednisone, Cortenema PM, 1g 5 ASA suppository AM


bookworm21
Veteran Member


Date Joined Mar 2008
Total Posts : 1766
   Posted 3/31/2009 6:23 AM (GMT -6)   
The dsDNA test came back negative as well. When I said the pain has gotten a bit worse, the only thing my PCP could offer was Pred and I said "absolutely not!" I have an appointment with a rheumy in May, so it's a bit of a wait.
Female, Age 20
9 Asacol, Rowasa1000 mg Canasa, Proctofoam, Rifaximin 2/day
Digestive Advantage (Crohn's & Colitis)1 Florastor, 50 mg 6MP,1 Primadophilus reuteri, Remicade (7 infusions), 2.4 g Lialda, Forvia, 6 Colazal, 1 Anucort, Culturelle, Fish Oil, Calcium/Vit D supplement, 20 mg Prozac, VSL #3 DS, Turmeric
 

New Topic Post Reply Printable Version
Forum Information
Currently it is Saturday, September 22, 2018 9:16 PM (GMT -6)
There are a total of 3,005,770 posts in 329,263 threads.
View Active Threads


Who's Online
This forum has 161801 registered members. Please welcome our newest member, kissel123.
302 Guest(s), 2 Registered Member(s) are currently online.  Details
GoBucks, Vdang2k