I have seen the literature re. 10-40 grams a day and to be honest, cannot fathom how that is possible without not having a bowel movement perhaps for many days, because even 5 grams or so is quite constipating, in my experience. Glutamine acts as a powerful diuretic: it diverts body fluid flow to the bladder, away from the colon. Hence it is powerful as an anti-diarrhea. However, in my experience it had no anti-inflammatory effects whatsoever- purely the diuretic effect. If I took more than 5 grams a day, I would often be blocked up for over 24 hours, all the while with no real stool forming. So tremendous pressure would build up inside with gas, etc., and pain would actually be worse. On top of this, I have come up on a couple studies in pubmed that indicated, paradoxically, that glutamine increased some measures of inflammation. I am skeptical but I will see about digging up the links. All I'd say is, be careful if you decide to try glutamine- start off with one or even half a minimal serving size a day- or less- and make sure it is not too constipating. I used to take it in small amoutns to slow down heavy D days but I don't take it for maintenance because I never noticed any effect on inflammation.
Pancolitis >20 years, allergic to all 5ASAs
Tried everything under the sun (natural and alternative)
Some partial success with TSO but was too expensive to keep up
Currently Remicade and lots of probiotics, tapering pred again, maybe surgery this year