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Scorpion24
Regular Member


Date Joined Mar 2009
Total Posts : 63
   Posted 3/26/2009 9:42 PM (GMT -6)   
L-Glutamine, how important is it? and how well does it work for our condition?

From the research I have done, it seems that the supplement is very useful for strengthening the large intestines by stimulating protective mucuosa and increasing the speed of recovery (healing).

PS. fish oils and omega-3 + omega-6 have been great for me and for most of us!

Dr-A
Veteran Member


Date Joined Jul 2006
Total Posts : 2105
   Posted 3/27/2009 6:36 AM (GMT -6)   
Several posts on it recently. I was told perque's version was about the best I could do with it. Has PAK.
Proctitis DX 1999, Pancolitis DX 2008
Lialda 1 day
Immuran
Golimumab study (100mg every 4 weeks)
Vitamin E Enemas as needed
Probiotis/GreenTea/VitD+Ca/SuperDHA


Mitzo
Veteran Member


Date Joined Dec 2007
Total Posts : 536
   Posted 3/27/2009 7:39 AM (GMT -6)   
It did nothing to help my persistent diarrhea.
23 years of UC which started after quitting smoking. In and out of flares which are usually triggered by antibiotics. Latest issue is endless diarrhea without blood or mucous.
  • Psyllium powder   
  • Cortenema


princesa
Veteran Member


Date Joined Aug 2007
Total Posts : 2204
   Posted 3/27/2009 9:30 AM (GMT -6)   
It's extremely important to help heal the gut and to help control diarrhea. It's also excellent for muscle building, since you're weight training, so you hit two birds with one stone.
 
Dr. Ronald Hoffman had this to say:

Specific benefit can be obtained from oral dosing with the amino acid L-glutamine. One study showed that seriously ill patients requiring intravenous feeding were more likely to wean themselves from dependency on nutritional supplementation by vein when given relatively high oral doses of L-glutamine on the order of one tablespoon three times daily, equivalent to 50 grams. L-glutamine may work as a direct "food" for intestinal cells in need of repair, as well as by virtue of the fact that it is a precursor for synthesis of the premier antioxidant glutathione.

 

Mitzo, how much were you taking?


Diagnosed with ulcerative colitis spring 1999.
 
Maintenance dose sulfasalazine. Probiotics, l-glutamine, vitamin D and fish oil caps. George's aloe vera juice. Oregano oil antibiotic, antiviral, antifungal. Mostly grain-free and dairy-free diet. Long-term remission with only minor blips.
 
 

Post Edited (princesa) : 3/27/2009 8:33:24 AM (GMT-6)


UCgoaway
Regular Member


Date Joined Feb 2009
Total Posts : 43
   Posted 3/27/2009 9:50 AM (GMT -6)   
princesa - 50 grams! I don't see any products that even come close to giving 50 grams. I most I saw was 5 grams per serving. How much do you take?
John, 32, diagnosed Jan. 23, 2009
 
Current Regimen:
 
3 x 3 Colazal
Rowasa every 3 nights
30mg BuSpar for GAD (made me super dizzy and restless)
25mg Zoloft for GAD
40mg Protonix
Forvia multivitamin
Align, Dr. Ohhira's, and S. Boulardii Probiotics
Turmeric, Boswellia, Fish Oil, and Milk Thistle (for my liver)
40, 30, 20, 10, 5mg Pred (tapering)


princesa
Veteran Member


Date Joined Aug 2007
Total Posts : 2204
   Posted 3/27/2009 2:00 PM (GMT -6)   
Notice he's talking about "seriously ill" people who are given "relatively high oral doses." Fifty grams is definitely on the high end.

You'll need at least 2-5 grams per serving to see obvious effects. Anywhere from 10-40 grams daily in divided doses will provide benefits in muscle building and retention, immune support and gut healing. You want the powder, not the capsules as you'd have to swallow too many to make up an effective dose. You have to take into account your weight and current health and listen to your body. If you feel sick or start to get constipated, you need to lower the dose.
Diagnosed with ulcerative colitis spring 1999.
 
Maintenance dose sulfasalazine. Probiotics, l-glutamine, vitamin D and fish oil caps. George's aloe vera juice. Oregano oil antibiotic, antiviral, antifungal. Mostly grain-free and dairy-free diet. Long-term remission with only minor blips.
 
 


UCgoaway
Regular Member


Date Joined Feb 2009
Total Posts : 43
   Posted 3/27/2009 2:02 PM (GMT -6)   
princesa - awesome...thanks!
John, 32, diagnosed Jan. 23, 2009
 
Current Regimen:
 
3 x 3 Colazal
Rowasa every 3 nights
30mg BuSpar for GAD (made me super dizzy and restless)
25mg Zoloft for GAD
40mg Protonix
Forvia multivitamin
Align, Dr. Ohhira's, and S. Boulardii Probiotics
Turmeric, Boswellia, Fish Oil, and Milk Thistle (for my liver)
40, 30, 20, 10, 5mg Pred (tapering)


Mitzo
Veteran Member


Date Joined Dec 2007
Total Posts : 536
   Posted 3/27/2009 7:58 PM (GMT -6)   
I was taking a teaspoon in a glass of water once a day for 3 weeks - no help, and I think I read somewhere that L glutamine may cause diarrhea in some cases?
23 years of UC which started after quitting smoking. In and out of flares which are usually triggered by antibiotics. Latest issue is endless diarrhea without blood or mucous.

 


Scorpion24
Regular Member


Date Joined Mar 2009
Total Posts : 63
   Posted 3/27/2009 9:47 PM (GMT -6)   
Thanks a lot, I will purchase it... although I will wait until my meeting with my N.D. which will run a few tests to see what certain foods cause problems in my intestines...
you rock princesa! cheers

LondonRed
Veteran Member


Date Joined Oct 2007
Total Posts : 1190
   Posted 3/28/2009 7:12 AM (GMT -6)   
After extensive research into many many things, I have found the following supplements are directly linked to help IBD:

VSL#3 or Natren Probiotic
L-Glutamin
Omega 3 Fish Oil
Vitamin D

That's what I now take and will keep everyone updated. I am also seeing a Homepathic on the UK Free Health Service. There has got to be a way out of this, God Willing.

Has anyone also tried Reiki? It is simply amazing but you must used a Reiki Master not just any one.

Diagnosis Oct 07 and then Aug 08: Inditerminate Patchy Colitis. Also suffer from Peptic Ulcers could be related to Asacol. Current Medication: 500mg Asacol Suppositories, 800mg Asacol Tablets x 2 a day.


princesa
Veteran Member


Date Joined Aug 2007
Total Posts : 2204
   Posted 3/28/2009 8:44 PM (GMT -6)   
Mitzo said...
I was taking a teaspoon in a glass of water once a day for 3 weeks - no help, and I think I read somewhere that L glutamine may cause diarrhea in some cases?

Actually, l-glutamine helps control diarrhea and, if anything, would be more likely to cause constipation at doses too high for the individual.
LondonRed said...
After extensive research into many many things, I have found the following supplements are directly linked to help IBD:

VSL#3 or Natren Probiotic
L-Glutamin
Omega 3 Fish Oil
Vitamin D

 
Yep, those are the things that have worked well for me and there's plenty of research and info out there on each one, explaining why they are helpful in the treatment of IBD.
Diagnosed with ulcerative colitis spring 1999.
 
Maintenance dose sulfasalazine. Probiotics, l-glutamine, vitamin D and fish oil caps. George's aloe vera juice. Oregano oil antibiotic, antiviral, antifungal. Mostly grain-free and dairy-free diet. Long-term remission with only minor blips.
 
 

Post Edited (princesa) : 3/28/2009 7:47:40 PM (GMT-6)


Probiotic
Veteran Member


Date Joined Mar 2007
Total Posts : 2832
   Posted 3/28/2009 10:00 PM (GMT -6)   

I have seen the literature re. 10-40 grams a day and to be honest, cannot fathom how that is possible without not having a bowel movement perhaps for many days, because even 5 grams or so is quite constipating, in my experience.  Glutamine acts as a powerful diuretic: it diverts body fluid flow to the bladder, away from the colon.  Hence it is powerful as an anti-diarrhea.  However, in my experience it had no anti-inflammatory effects whatsoever- purely the diuretic effect.  If I took more than 5 grams a day, I would often be blocked up for over 24 hours, all the while with no real stool forming.  So tremendous pressure would build up inside with gas, etc., and pain would actually be worse.   On top of this, I have come up on a couple studies in pubmed that indicated, paradoxically, that glutamine increased some measures of inflammation.  I am skeptical but I will see about digging up the links.  All I'd say is, be careful if you decide to try glutamine- start off with one or even half a minimal serving size a day- or less- and make sure it is not too constipating.  I used to take it in small amoutns to slow down heavy D days but I don't take it for maintenance because I never noticed any effect on inflammation.

 


Pancolitis >20 years, allergic to all 5ASAs
Tried everything under the sun (natural and alternative)
Some partial success with TSO but was too expensive to keep up 
Currently Remicade and lots of probiotics, tapering pred again, maybe surgery this year
 
 

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