Prednisone lowest dosage to get out of flare

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therearemiracles
Veteran Member


Date Joined Dec 2006
Total Posts : 3670
   Posted 4/2/2009 8:16 AM (GMT -6)   
Hi it was recommend that I try 10mg of Pred to get out of flare i'm in. I've never been on it, what's the lowest dose out there and would it help? I turned in my stool test, results will be on Monday to see why I'm going to the bathroom so much. It could be UC but I went to Mexico in Feb and my symptoms seem worse.
Thank you,
Very mild left sided (could have fooled me with the "mild")  UC. STARTED LDN ON 1/25/09. Supplements:  Cod Liver, Probiotics, multi whole food vitamin, olive leaf extract.


Rio in Maryland
Veteran Member


Date Joined Nov 2007
Total Posts : 891
   Posted 4/2/2009 8:27 AM (GMT -6)   
10 mg is a low dose to start on, but depending on your symptoms and response to medicines, your doctor probably thinks that's the best route for you.

The lowest tablet dose of prednisone that I have seen is 5 mg; but the final dose that you end up taking can be lower as when tapering down to very low levels I have split tablets in half, or taken a tablet only on alternate days to get it to even out to 2.5 mg a day.

Have you tried taking rectal meds?
Rio, 33 year old male. Diagnosed with UC in 2006
100 mg Azathioprine, 4800 mg Asacol
VSL#3 x 3 times a day, Metamucil wafers
Vitamin E enema or Mesacol/Asacol enema at least once a week
Spinach & sunflower seed diet


therearemiracles
Veteran Member


Date Joined Dec 2006
Total Posts : 3670
   Posted 4/2/2009 8:33 AM (GMT -6)   
I don't know what it is, but the 5ASA, asacol, colozal, canasa all make me so sick, my symptoms get worse. My butt is raw and when I go to the bathroom, any time I eat anything, just to (sorry to be gross) open up my butt to go is like glass. Does prednisone seem to work fairly quickly?

Very mild left sided (could have fooled me with the "mild")  UC. STARTED LDN ON 1/25/09. Supplements:  Cod Liver, Probiotics, multi whole food vitamin, olive leaf extract.


Rio in Maryland
Veteran Member


Date Joined Nov 2007
Total Posts : 891
   Posted 4/2/2009 8:42 AM (GMT -6)   
Yes, one of the benefits of prednisone is that it typically works very quickly.

You could also try cortifoam before starting on prednisone. Cortifoam shouldn't be too rough on your butt. Also, I tried Vitamin E enemas and those worked well for me.
Rio, 33 year old male. Diagnosed with UC in 2006
100 mg Azathioprine, 4800 mg Asacol
VSL#3 x 3 times a day, Metamucil wafers
Vitamin E enema or Mesacol/Asacol enema at least once a week
Spinach & sunflower seed diet


Peety
Veteran Member


Date Joined Mar 2008
Total Posts : 2855
   Posted 4/2/2009 10:59 AM (GMT -6)   
If you don't notice any improvement in a day or two, it probably means it's either not a big enough dose, or you have an entirely different problem that the prednisone will not help.
49 year old female attorney, diagnosed UC/pancolitis 1985, no surgery but much suffering. Asacol/5ASA 6x400 mg maintenance for 20+ years; use prednisone & Rowasa for flares. 
August 2008 sought care of naturopathic doctor. Food sensitivity test showed wheat/gluten, other intolerances; eliminated all wheat/gluten from my diet. Probiotics (Ultimate Flora, 50 billion), trying Curamin. 
Flaring, seasonal? or supplements too harsh? Back on prednisone, tried to taper but now back up to 20-30 after several really bad days. Waiting for insurance decison on Humira...soon... 


glamourgirl
Regular Member


Date Joined Apr 2008
Total Posts : 460
   Posted 4/2/2009 1:03 PM (GMT -6)   
Maybe you could try the steroid enemas first. I just started them 2 nights ago and after the first night, I felt so much better. I'm not sure that 10 mg or prednisone will help, usually 40 mg. is the starting point. Whenever I've taken prednisone, I get relief after a few days but that's at 40 mg.
Female, Age 38
Diagnosed w/c.diff 7/02 when pregnant w/1st and only child during 2nd trimester(wasn't on antibiotics)
C.diff flare within weeks of delivering baby 1/03, Diagnosed with UC 2/03
Current Meds:
LDN - 2/17/09 1.5 mg., increased to 3 mg. 3/3/09
Ferrex Forte
Acidophillus, Sacchromyces Boulardii, Oil of Oregano

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