ASACOL and our kidneys???

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Mia @;------
Regular Member


Date Joined Feb 2007
Total Posts : 231
   Posted 4/3/2009 7:35 AM (GMT -6)   
Has anyone experienced and kidney problems or complications due to prolonged use of ASACOL?
 
Female
Diagnosed in 2001,
Since then i have flared seven times, each time taking 40mg of pred for a month to manage the flare. Now on my eighth dose since diagnosis!
Currently on Asacol 6 tabs a day
 
 


gaff
Regular Member


Date Joined Jul 2006
Total Posts : 442
   Posted 4/3/2009 7:56 AM (GMT -6)   
YES! Asacol damaged a friend's kidneys to a point were they only function at 40% I think.
gaff
left-sided UC since 11/05
 Rowasa, Colazal, Calcium, Centrum
Natren Healthy Trinity Probiotics


Mia @;------
Regular Member


Date Joined Feb 2007
Total Posts : 231
   Posted 4/3/2009 8:17 AM (GMT -6)   
Really!!!!!Im sooo worried at the moment, ive been have continous urine infections since october, i had a scan and results show a slightly enlarged kidney.. The doctor said more tests need to be done as it maybe obstrcuted!Im so worried, Ive had so much bad new this year i cant take no more... Do you think in it wise to stop the tablets cold turkey? What has your friend had to do?
Female
Diagnosed in 2001,
Since then i have flared seven times, each time taking 40mg of pred for a month to manage the flare. Now on my eighth dose since diagnosis!
Currently on Asacol 6 tabs a day
 
 


Mia @;------
Regular Member


Date Joined Feb 2007
Total Posts : 231
   Posted 4/3/2009 8:18 AM (GMT -6)   
Really!!!!!Im sooo worried at the moment, ive been have continous urine infections since october, i had a scan and results show a slightly enlarged kidney.. The doctor said more tests need to be done as it maybe obstrcuted!Im so worried, Ive had so much bad new this year i cant take no more... Do you think in it wise to stop the tablets cold turkey? What has your friend had to do?
Female
Diagnosed in 2001,
Since then i have flared seven times, each time taking 40mg of pred for a month to manage the flare. Now on my eighth dose since diagnosis!
Currently on Asacol 6 tabs a day
 
 


gaff
Regular Member


Date Joined Jul 2006
Total Posts : 442
   Posted 4/3/2009 9:10 AM (GMT -6)   
It took him awhile to convince the doc that there was a problem.. I would call your GI and see if you can switch to something else, like Colazal or one of the other drugs.
gaff
left-sided UC since 11/05
 Rowasa, Colazal, Calcium, Centrum
Natren Healthy Trinity Probiotics


Mia @;------
Regular Member


Date Joined Feb 2007
Total Posts : 231
   Posted 4/3/2009 9:31 AM (GMT -6)   
I've just spoken to my nurse and she said my blood test results show normal levels of creatine and protien... Im confused at what to think or do!
How long was your friend on the tabs for?I've been using them for abt 5 yrs now, i guess im going to have to wait for further tests to get a definate answer...
Female
Diagnosed in 2001,
Since then i have flared seven times, each time taking 40mg of pred for a month to manage the flare. Now on my eighth dose since diagnosis!
Currently on Asacol 6 tabs a day
 
 


fargman
Regular Member


Date Joined Dec 2008
Total Posts : 74
   Posted 4/3/2009 11:11 AM (GMT -6)   
I've been on Asacol for 10 years and have had no problems with my kidneys.
Diagnosed '93. 
 
Asacol, Prednisone, Remicade, Imuran
 


subdued
Veteran Member


Date Joined Dec 2008
Total Posts : 3231
   Posted 4/3/2009 11:36 AM (GMT -6)   
gaff said...
It took him awhile to convince the doc that there was a problem.. I would call your GI and see if you can switch to something else, like Colazal or one of the other drugs.


Colazal may also cause kidney damage. That's why I decided not to take maintenance drugs. The possible side effects of long-term use are worse than getting the colon taken out.
Joy - 47 yrs and counting
Colitis Dec 06 (also have IBS)
Currently in remission
Don't expect your doctor to cure your health problems. Your health is your responsibility.

Lexapro (for stress), Probiotics and Vitamins (a whole bunch of them)
Avoid HFCS, foods high in fructose, artificial sweeteners
When flaring: eat anti-inflammatory foods, avoid pro-inflammatory foods
Previous treatments: Fecal transplantation (worked), Prednisone (stopped working), Colazal (stopped working), Asacol (stopped working)


Christine1946
Veteran Member


Date Joined Aug 2008
Total Posts : 5965
   Posted 4/3/2009 2:02 PM (GMT -6)   
     Long term use of these drugs scares me too, but, I went off the Colazal and 6MP twice in the past and twice I suffered flares from doing so.
62 yr old granny. South Jersey
Diagnosed with ulcerative proctitis in 1998 in hospital
Hospitalized (2nd time) in May 2008
Update 11/03/08...finally in remission!!  Hope I don't jinx myself.  Off the prednisone since 11/01/08...now see if I can stay off for longer than two weeks.  Other meds: 6MP (75 mgm), colazal (6 per day), Benicar and Toprol (high blood pressure meds), Probiotic (2 per day), fish oil capsule and multi-vitamin and calcium with vitamin D.


fruitgirl
Veteran Member


Date Joined Feb 2009
Total Posts : 7150
   Posted 4/3/2009 2:09 PM (GMT -6)   
Have you been having a lot of diarrhea lately? That could be why you've had so much trouble with UTIs...all that extra pooping results in a lot more bacteria floating around "down there," which can increase your chances of getting a UTI. Also, on a very personal note, has anything changed in your sex life? I had recurrent UTIs so my doctor finally wrote me an Rx for macrobid to take one pill after sex. I've not had one UTI since starting that.
Symptoms began in November 2008, ~4 weeks after giving birth to my son.
Eased for ~3 weeks in December, possibly b/c of probiotic use?
Returned in January 2009 (with a vengeance), diagnosed with pancolitis on January 30.
Currently taking Asacol (400mg 4 pills 3x daily), Rowasa nightly, 40mg 30mg 20mg 15mg of Prednisone (quick taper), Culturelle probiotic, and Zoloft (25 mg).


Mia @;------
Regular Member


Date Joined Feb 2007
Total Posts : 231
   Posted 4/3/2009 4:03 PM (GMT -6)   

I have had diarrhea lately, but no more than i've had in the past. I've had four infections in the space of 6 months which is why i was issued with a scan, and one of my kidneys showed to be slightly enlarged, which worries me. As there may be a possibility it is obstructed which is why im due for more tests.

As for my sex life its not changed i've been with the same partner etc.

Is it not risky to take antibiotics everytime you have sex?

I just want answers and this all to stop! :(


Female
Diagnosed in 2001,
Since then i have flared seven times, each time taking 40mg of pred for a month to manage the flare. Now on my eighth dose since diagnosis!
Currently on Asacol 6 tabs a day
 
 


fruitgirl
Veteran Member


Date Joined Feb 2009
Total Posts : 7150
   Posted 4/3/2009 4:14 PM (GMT -6)   
Well, my problems with UTIs started long before I had problems with UC, so at that point, it was much more risky for me to keep getting UTIs (and therefore keep being put on antibiotics for 10 days to 2 weeks) than it would be to take one pill each time. I haven't discussed it with my GI, but I probably should. I don't think that one pill would cause me too many problems, though, because I do take a probiotic each day and I don't think my UC started as a result of a bacterial imbalance.
Symptoms began in November 2008, ~4 weeks after giving birth to my son.
Eased for ~3 weeks in December, possibly b/c of probiotic use?
Returned in January 2009 (with a vengeance), diagnosed with pancolitis on January 30.
Currently taking Asacol (400mg 4 pills 3x daily), Rowasa nightly, 40mg 30mg 20mg 15mg of Prednisone (quick taper), Culturelle probiotic, and Zoloft (25 mg).


Peety
Veteran Member


Date Joined Mar 2008
Total Posts : 2855
   Posted 4/3/2009 4:44 PM (GMT -6)   
I always thought it was prednisone that could cause kidney problems, so I don't know how you would know what caused what.

Sometimes I would worry back pain was a kidney problem and would get tested ----but always test clean, fortunately.
49 year old female attorney, diagnosed UC/pancolitis 1985, no surgery but much suffering. Asacol/5ASA 6x400 mg maintenance for 20+ years; use prednisone & Rowasa for flares. 
August 2008 sought care of naturopathic doctor. Food sensitivity test showed wheat/gluten, other intolerances; eliminated all wheat/gluten from my diet. Probiotics (Ultimate Flora, 50 billion), trying Curamin. 
Flaring, seasonal? or supplements too harsh? Back on prednisone, tried to taper but now back up to 20-30 after several really bad days. Waiting for insurance decison on Humira...soon... 


fruitgirl
Veteran Member


Date Joined Feb 2009
Total Posts : 7150
   Posted 4/3/2009 5:07 PM (GMT -6)   
Peety, Asacol can be hard on the kidneys. My sis is a pediatric nephrologist (kidney specialist) and she said that I need to avoid NSAID pain releivers as much as possible, especially when I'm in a flare and possibly a bit dehydrated, as they are also tough on the kidneys.
Symptoms began in November 2008, ~4 weeks after giving birth to my son.
Eased for ~3 weeks in December, possibly b/c of probiotic use?
Returned in January 2009 (with a vengeance), diagnosed with pancolitis on January 30.
Currently taking Asacol (400mg 4 pills 3x daily), Rowasa nightly, 40mg 30mg 20mg 15mg of Prednisone (quick taper), Culturelle probiotic, and Zoloft (25 mg).


subdued
Veteran Member


Date Joined Dec 2008
Total Posts : 3231
   Posted 4/3/2009 5:31 PM (GMT -6)   
I don't know whether or not there is a connection or if it was just a coincidence, but I never had a bladder infection until after I had taken Colazal and Asacol.

I would rather get my colon taken out then take the chance of messing up my kidneys.
Joy - 47 yrs and counting
Colitis Dec 06 (also have IBS)
Currently in remission
Don't expect your doctor to cure your health problems. Your health is your responsibility.

Lexapro (for stress), Probiotics and Vitamins (a whole bunch of them)
Avoid HFCS, foods high in fructose, artificial sweeteners
When flaring: eat anti-inflammatory foods, avoid pro-inflammatory foods
Previous treatments: Fecal transplantation (worked), Prednisone (stopped working), Colazal (stopped working), Asacol (stopped working)


Scorpion24
Regular Member


Date Joined Mar 2009
Total Posts : 63
   Posted 4/3/2009 7:24 PM (GMT -6)   
What can I say, asacol has its side effects and every medicine will hurt certain individuals to a certain extent!

The fact is that it may or may not... try to maintain a healthy life style and hope for the best, what else can we do

mbx5
Regular Member


Date Joined Sep 2007
Total Posts : 365
   Posted 4/3/2009 8:40 PM (GMT -6)   
I have a cyst in my right kidney, and also have chronic kidney stones....not sure its related to Asacol....I have been on and off Asacol for many years. My GI doesnt think it is related. Currently I am having one of my stones analyzed for its cause...
34 yr old male. UC for 14 years. Started left-sided, most recent scope shows pancolitis. 30mg pred (as of 2/01/09), 12x pills Asacol per day, 1mg Atavan per day (anxiety) when needed, 20mg paxil per day, Super-omega fish oil pills - 1x per day, Flax oil pills - 1x am, 1x pm, Culturelle probiotics - 2x am, 1x pm, Spinach and sunflower seed diet (moderated recently due to kidney stones). Multivitamin. Recent Endonasal brain surgery to remove non-cancerous hormone producing tumor on pituitary gland (and I am still more afraid of my UC!!) "I poop in the woods because I can"


Old Hat
Veteran Member


Date Joined Feb 2007
Total Posts : 5182
   Posted 4/3/2009 8:45 PM (GMT -6)   
Drink plenty of water throughout the day to help protect your kidneys. It seems from the lab results that you're not leaking protein-- that's a condition to be avoided. Another member here, Beth75, has posted in the past about her need for treatment of major kidney complications, in case you want to look up her comments. / Old Hat (30 yrs with left-sided UC ... [etc.])

Mia @;------
Regular Member


Date Joined Feb 2007
Total Posts : 231
   Posted 4/4/2009 6:47 AM (GMT -6)   
Thanks guys and gals, hopefully i get the tests done soon to set things straight!

Diagnosed in 2001,
Since then i have flared seven times,
Currently on Asacol 6 tabs a day. Recently diagnosed with osteopenia.
 
 

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