You should never just "go off" the prednisone. It has to be tapered. If not, it can have very debilitating results. My friend wound up with Addison's Disease from doing so.
62 yr old granny. South Jersey
Diagnosed with ulcerative proctitis in 1998 in hospital
Hospitalized (2nd time) in May 2008
Update 11/03/08...finally in remission!! Hope I don't jinx myself. Off the prednisone since 11/01/08...now see if I can stay off for longer than two weeks. Other meds: 6MP (75 mgm), colazal (6 per day), Benicar and Toprol (high blood pressure meds), Probiotic (2 per day), fish oil capsule and multi-vitamin and calcium with vitamin D.