I was under the impression that Remicade induced lupus is fairly common- I could be totally wrong though! It's just that I've heard of a fair amount of people who've developed it. That's yet another of my many Remicade worries. Lots of conditions can be drug induced, Christine- I had drug induced hepatitis while in the hospital. Once you stop the offending drug, the condition usually goes away. Oh yeah, I had drug induced diabetes too! But anyway, god ediekristen, that SUCKS! I hope for your sake it isn't the lupus- you'd have no choice but to go off Remicade if it was. Even an infection while on Remicade can be a nasty nasty thing! Please let us know what your GI says- you may want to give him/her a ring prior to seeing your primary care doc, just run it by him- he may want you to see him instead. Take care!