I don't think it is advisable to break the dosage. I have always been advised by all my doctors that it should be taken in the morning only, and if possible with milk. They were of the view that the Pred taken in one dosage is more effective. If you take it in the evening, or at bed time, it is likely to cause more side effects, in some cases.
There are lots of threads on HW on this issue. Please go through the same before you embark upon any decision.
45 years Male Attorney
Diagnosed UC October 1989
Had two stage J Pouch Surgery Nov 2005; Take Down March 2006
Complications after surgery - Incisional Hernia and Ano Fistulas
"There are only two ways to live your life. One is as though nothing is a miracle. The other is as though everything is a miracle: Albert Einstein
"What you are aware of you are in control of; what you are not aware of is in control of you."