I also had this problem before my doctor started me on 6MP. Ask your doctors about it. You must take it along with the prednisone, as it takes anywhere from three to six months to "kick in". There are side effects but your doctor should go over them with you completely. You will be required to receive monthly CBC's to monitor your white count. Right now mine is 2.9, not too happy about it being that low, but it keeps your immune system from attacking itself and my GI doctor isn't too alarmed. However, I cut my dosage from 75 mgm to 50 mgm one day and 25 mgm the next. Since I did this my white count did improve somewhat...it was 2.4. I am scheduled for another blood work up next week. This will include not only the CBC but liver enzyme tests and pancreatic enzyme levels. Living with this disease is mind boggling at times...but look at it this way...we are LIVING with it. Oh, I might add, I was able to get off the prednisone Nov 1st and have been in full remission ever since. It was a long seven month flare last year.
62 yr old granny. South Jersey
Diagnosed with ulcerative proctitis in 1998 in hospital
Hospitalized (2nd time) in May 2008
Update 11/03/08...finally in remission!! Hope I don't jinx myself. Off the prednisone since 11/01/08...now see if I can stay off for longer than two weeks. Other meds: 6MP (75 mgm), colazal (6 per day), Benicar and Toprol (high blood pressure meds), Probiotic (2 per day), fish oil capsule and multi-vitamin and calcium with vitamin D.