Do you refuse all antibiotics??

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New Member

Date Joined Apr 2009
Total Posts : 4
   Posted 4/28/2009 11:46 AM (GMT -6)   
To avoid C-Diff??

Regular Member

Date Joined Apr 2009
Total Posts : 249
   Posted 4/28/2009 12:10 PM (GMT -6)   
just wondering what c-diff is.
Diagnosed with Crohns in October 07
Diagnosed by new dr with Ulcerative Colitis 03/09
Colonoscopy on 4/23-diagnosed with severe ulcerative proctitus
12 Asacol/day
prednisone (20 mg) - until can get bleeding under control
waiting for lab work so I can start Imuran

Veteran Member

Date Joined Jun 2008
Total Posts : 2865
   Posted 4/28/2009 12:19 PM (GMT -6)   

The answer is NO.  I have been tested for c-diff twice because I flared badly after two weeks on amoxicillin.  Here is a very good site all about c-diff.  There are antibiotics that fight c-diff and others you can take that won't give you c-diff.  I always ask my doctor and find that I can take several now.



Senior - New diagnosed with proctosigmoiditis - 6/2008   Tried, Colozal, steroid enemas, etc. - started working but severe side effects occurred. No mesalamines!!
Started on prednisone Feb.7, 2009 - tapering to 20 mg. - upped prenisone to 25mg. on my own (bleeding returned) - 6MP - 50 mg. 2/28/2009 
75mg. 6 MP added on 4/8/2009 - waiting for CBC and Prometheus tests
Probiotic Align, Prilosec for GERD, Gas-X, vitamins, Calcium/D
Tylenol for knees and arthritis.

Elite Member

Date Joined Mar 2003
Total Posts : 10407
   Posted 4/28/2009 12:20 PM (GMT -6)   
C-diff is clostridium dificile, a bacteria that causes "opportunistic" infections. IBD-ers get it more commonly because UC can kill off the normal bacteria in your colon, and c. diff can move in. It causes severe watery diarrhea, cramping and fever. Because antibiotics also kill off intestinal bacteria, they can make you more susceptible also.

I don't refuse antibiotics. I do make sure that all my doctors know I have UC, but then I've always been cautious about taking antibiotics if they aren't really needed because of the resistance issue. When I do need abx, I negotiate what kind I'll take. If possible, I try to use Azithromycin because it is only a five-day course so has less opportunity to make me sick.

I also double up on my probiotics when on abx. Be sure to take them at least 2 hours after and 4 hours before a dose of antibiotics.
Moderate to severe left-sided UC diagnosed 2001.
Flared for 5 years, finally in remission with Remicade since March 2006.
Avascular necrosis in both shoulders is my "forever" gift from steroids.
Colazal,  Remicade, Nature's Way Primadophilus Reuteri. 
"My life is an ongoing medical adventure"

Veteran Member

Date Joined Mar 2008
Total Posts : 678
   Posted 4/28/2009 12:25 PM (GMT -6)   
I would try to avoid antibiotics b/c of my UC. That's what stirred up my UC for me in Feb.
31 yr old female currently breastfeeding (weaning so I can start 6mp)
Mild Pancolitis
I've had UC since 2000 but was in remission for most of those 8 years med free
Cannot tolerate mesalamine - starting 6mp soon

Regular Member

Date Joined Apr 2009
Total Posts : 31
   Posted 4/28/2009 12:30 PM (GMT -6)   
C-diff is a nasty infection which is extremely prevalent now in the hospital setting and now in the community as well. THere was a big article about it in the NY Times 3 weeks ago.

the infection is actually caused by the toxin which is released by the bacteria that has overwhelmed the gut from imbalance of the flora.
Abx can cause this infection. One of the most notorious of them is Clindamycin, but almost all of them can cause it.
definitely take extra probiotix if u require abx to decrease chances of c-diff.
Ghena 31 UC

Veteran Member

Date Joined Feb 2009
Total Posts : 7150
   Posted 4/28/2009 12:36 PM (GMT -6)   
I've never taken antibiotics unless it's absolutely necessary. If I have a cold/sinus issue, I'll wait until I've been sick for over two weeks before I'll even go to a doctor. However, if I know I have an infection, such as a UTI, I'll definitely take antibiotics, because an infection left untreated can cause huge problems.
Symptoms began in November 2008, ~4 weeks after giving birth to my son.
Eased for ~3 weeks in December, possibly b/c of probiotic use?
Returned in January 2009 (with a vengeance), diagnosed with pancolitis on January 30.
Currently taking Asacol (400mg 4 pills 3x daily), Rowasa nightly, Culturelle probiotic, and Zoloft (25 mg).

Veteran Member

Date Joined Feb 2005
Total Posts : 2103
   Posted 4/28/2009 1:41 PM (GMT -6)   
I swear that flagyl caused my initial flare (I didn't have c-diff from it). When I was a baby I had an infection of some sort and took antis too long and it killed off everything and I was in the hospital for a week or so. That happened again the summer before I was diagnosed when I was taking flagyl for an h-pylori infection and I think that happening twice in my life was just too much for my colon.
Now I'm not totally afraid of antis. I make sure my dr is aware of my UC and then ask for z pack. I also take a probiotic to ensure I have enough gut flora.
20 year old college student diagnosed in March 2005
Remission since January/April 2006->THREE YEARS!!!!!
Trying Colazal 3 750mg x2 (NOT for a full blown flare, just some random symptoms)
25mg Elavil
75mg Effexor XR for GAD
Will possibly go back to asacol
"If you don't like something, change it. If you can't change it, change your attitude."
Maya Angelou

Regular Member

Date Joined Apr 2008
Total Posts : 460
   Posted 4/28/2009 4:48 PM (GMT -6)   
How would one refuse an antibiotic if they had an infection? I don't take antibiotics unless absolutely necessary but sometimes they are a must. I get UTI's and the only way to get rid of them is with an antibiotic. I got c.diff before I had UC and I wasn't on antibiotics. It took 3 months for it to go away. I now get it about once a year. I wish it were as simple as refusing antibiotics but it's just not always an option.
Female, Age 38
Diagnosed w/c.diff 7/02 when pregnant w/1st and only child during 2nd trimester(wasn't on antibiotics)
C.diff flare within weeks of delivering baby 1/03, Diagnosed with UC 2/03
Current Meds:
Lialda, 6MP
Ferrex Forte
Acidophillus, Sacchromyces Boulardii, Oil of Oregano

Veteran Member

Date Joined Dec 2008
Total Posts : 3231
   Posted 4/28/2009 5:03 PM (GMT -6)   
It depends on what the antibiotics are for. Some infections will cure themselves on their own. I'll take antibiotics if they are for a bladder infection, which can result in kidney damage if left untreated. I now take cranberry supplements and don't use spermicide to reduce the likelihood of getting another bladder infection.

I have asked for antibiotics that aren't as harmful to the colon, but they ended up not working.
Joy - 47 yrs and counting
Colitis Dec 06 (also have IBS)
Currently in remission
Don't expect your doctor to cure your health problems. Your health is your responsibility.

Lexapro (for stress), Probiotics and Vitamins (a whole bunch of them)
Avoid HFCS, foods high in fructose, artificial sweeteners
When flaring: eat anti-inflammatory foods, avoid pro-inflammatory foods
Previous treatments: Fecal transplantation (worked), Prednisone (stopped working), Colazal (stopped working), Asacol (stopped working)

Elite Member

Date Joined May 2003
Total Posts : 30986
   Posted 4/29/2009 1:17 AM (GMT -6)   
If I have to take them for an infection (chest/ larynx/ sinus)....I do. I've never taken antibiotics for my colon, however....I've never been on Flagyl.
C. diff is in all our's just kept in check from other bacteria.  C.diff can also be taken in from hand to mouth.....ugh.
One should be on probiotics regardless....and probably up them a bit if ever on antibiotics.


*Heather* Status: mild flare enemas tapered to every 2nd night
~diagnosed January 1989 UC (proctosigmoiditis)
~UC meds: Asacol (3 x2 daily); Salofalk enemas nightly for flares & taper to maintenance 
~Bentylol (dicyclomine) 20mg as needed; Ranitidine (reflux);  Effexor XR 75mg(depression);  Pulmicort/Airomir (asthma) 
~vitamins/minerals/supplementsProbiotics....(Natural Factors Protec, Primadophilus Reuteri Pearls, Natural Factors Ultimate). @ bedtime
~various digestive enzymes as needed; started Omega 3 
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS"  worth it !!!

Elite Member

Date Joined Apr 2004
Total Posts : 23551
   Posted 4/29/2009 6:25 AM (GMT -6)   
I'm the same, I don't take them unless absolutely necessary and if I do have to take them I take Zithromyacin because that doesn't seem to affect my Uc any - but like stated, it depends on the infection as to what antibiotic/antifungal to take. I've had C. Diff before and it was NOT fun. I was going to the bathroom up to 30-40 times a day and lordy was I sore! Luckily I responded well to whatever treatment they gave me - can't remember because this was about 15 years ago.
Moderator for Allergies/Asthma and Co-moderator for UC
~Left sided Uc-'92-Colazal(9 daily),6mp(50-100mgs),Bentyl, Prilosec,Biotin,Forvia,Pro-Bio**Unable to tolerate Asacol, Rowasa or Canasa**~Year-round allergies-Singulair, Zyrtec~Secondary Reynauds Syndrome-'04-Norvasc~Sacroiliitis-epidural injections~bulging and herniated discs C5/C6 & C6/C7~3 epidural injections-second series starts 2/17, OA in my fingers -Celebrex, Tylonel Arthritis and Voltaren Gel
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