I was diagnosed with UC about a year ago, and I'm currently on my second course of steroids. I currently live in Japan, but I plan to go on a cycling trip across South East Asia in a few months. I need to keep taking the enemas, but they are, of course, impossible to carry with me on a bike (the trip will take months!) so I need a portable solution.
My plan is to use a small bulb syringe (or douche) and to crush generic Mesalamine to a powder, and suspend it in mineral/filtered water.
There are unknowns here.... Please advise if you can.
1. Is it dangerous to use mineral/filtered water in place of ph neural or saline?
2. I understand that the tablets have microcapsules, which only deliver their payload when coming into contact with bacteria in the intestines. Is this true?
3. If #2 is true, then will crushing a tablet using a pestle and mortar be sufficient to release the useful drugs, or, will the capsules still come into contact with the relevant bacteria in the lower intestines, if injected in solution?
4. I can see particles floating around inside the Pentasa enemas I am prescribed. Is this the same as a Pentasa capsule that has been crushed, or different!?
Many thanks for any suggestions or criticisms.