Starting my third month tomorrow. So far I don't know if it is working at all. I tapered from 40 mg. of prednisone down to 20 and then bleeding and pain started again so I went back up to 25 mg. Then doctor raised 6 MP to 75mg. but I had to back off because of side effects. Still not really sure where side effects are coming from so may have to try 75Mg again to find out. I got dizzy when laying down, nauseated, muscle aches, ringing ears, headaches, and feeling "blah" which got better when I back down to 50 mg. I am very sensitive to medication and cannot tolerate any mesalamines.
So, after a couple weeks of 25 mg. I went down to 20 mg. and after three days - bleeding again (had stopped for a while mostly). Waiting to hear about blood tests, etc. Be sure you have your blood tested regularly. I was told it would take 3 to 6 months probably to "kick in". I wish it would so I could go further down with the prednisone.
Senior - New diagnosed with proctosigmoiditis - 6/2008 Tried, Colozal, steroid enemas, etc. - started working but severe side effects occurred. No mesalamines!!
Started on prednisone Feb.7, 2009 - tapering to 20 mg. - upped prenisone to 25mg. on my own (bleeding returned) - 6MP - 50 mg. 2/28/2009
75mg. 6 MP added on 4/8/2009 - waiting for CBC and Prometheus tests
Probiotic Align, Prilosec for GERD, Gas-X, vitamins, Calcium/D
Tylenol for knees and arthritis.