Most doctors recommend that you stay on it indefinitely. But my GIs have said that I can try to wean off of it and see if I can stay in remission with just Colazal. Which sounded like a good option when I was scared to death of taking Remicade. But now that I'm living a semi-normal life and have gotten comfortable being in remission, I'm not sure I want to give up Remicade and risk the chance of having to get surgery. And yes, there are more chances that it will not work after stopping it.
I've heard of doctors starting Imuran or 6MP at the same time as Remicade, and then getting off the Remicade a few months later when Imuran/6MP has kicked in.
Female, Age 20
9 Asacol, Rowasa, 1000 mg Canasa, Proctofoam, Rifaximin 2/day
Digestive Advantage (Crohn's & Colitis), 1 Florastor, 50 mg 6MP, 1 Primadophilus reuteri, Remicade (7 infusions), 2.4 g Lialda, Forvia, 6 Colazal, 1 Anucort, Culturelle, Fish Oil, Calcium/Vit D supplement, 20 mg Prozac, VSL #3 DS, Turmeric