In my state, there is an insurer of last resort who must take all applicants. I think -- think -- there is an upper limit to the amount this company can charge, but I imagine the premiums are still pretty high.
When I was self-employed, group insurance required five employees, which wasn't feasible for me. Too, I imagine getting the funds to start a business in this economic climate is going to be difficult.
For the longest time, I had an medical insurance policy with a fair deductible which kept the monthly premiums reasonable. But I went into it in good health, so the premiums could not be raised when I was diagnosed with UC.
If I were 25 and in fairly good health and really wanted to follow my dream, I might consider winging it without insurance. (And maybe doing something you love will help you feel better, too.) Especially if you think you can get a job with group insurance at some time in the future, you've got your whole life to be chained to a desk.
Every time I added up premiums and co-pays and deductibles I was paying more for the insurance than the insurance was paying the doctors -- even with UC. The scripts are another matter. Have you considered sulphasalazine? It's probably about $50 a month.
With that in mind, have you condsidered a catastrophic policy which should be fairly inexpensive but would only cover you in a serious emergency?