By twice a day, do you mean the dosage you're at? or to just drop 3 out of your daily regimen?
I would think that with your slight inflammation, you could reduce the dosage somewhat....maybe to 6...eventually....but you would have to taper to there.
I've taken twice a day for 20 years.....I've pretty much stayed at 6 for most of it, and increased once to 8 daily for a few months, then tapered back down to 6.
You could do 8 daily....4 morning, 4 evening. If you were wanting to taper to 6, you should only drop one pill a week...so, it'll take a few weeks.
You should also be on rectal meds to get the lower part of the rectum inflammation down and then taper them to maintenance.
One thing, finding a maintenance level will allow you to increase during flares if you need to...but I would think that all you might need is to increase rectal meds. If the supps aren't enough, then the enemas would be your next decision.
*Heather* Status: mild flare enemas tapered to every 3rd night
~diagnosed January 1989 UC (proctosigmoiditis)
~UC meds: Asacol (3 x2 daily); Salofalk enemas nightly for flares & taper to maintenance
~Bentylol (dicyclomine) 20mg as needed; Ranitidine (reflux); Effexor XR 75mg(depression); Pulmicort/Airomir (asthma)
~vitamins/minerals/supplements; Probiotics....(Natural Factors Protec, Primadophilus Reuteri Pearls). @ bedtime
~various digestive enzymes as needed
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS" worth it !!!