I think you have a few options before trying azathriopine.
First, have you been using ANY rectal meds? I started off just on Asacol (12 pills/day split over 3 doses), but a week later my doctor added Rowasa enemas. Even though I have pancolitis, they helped a lot as the Asacol doesn't necessarily make it all the way to the rectum, and if that's not healed, you can still be having really bad symptoms. Don't think that rectal meds won't work just because they don't reach that far into the colon...studies have shown that they are much more effective at healing inflammation than oral meds are. With Asacol and Rowasa, I was getting to remission, but then I got a tummy bug that really set me back. So, I did pred (a quick course by traditional standards) and it worked well for me.
Second, I think you could try a higher starting dose of pred (60mg) and then do a slower taper. Sometimes it takes that high of a starting dose to get rid of the inflammation.
There is a good chance the azathriopine will work even though the prednisone didn't.
Also, I would definitely talk to your doctor about
Remicade before talking about
Symptoms began in November 2008, ~4 weeks after giving birth to my son.
Eased for ~3 weeks in December, possibly b/c of probiotic use?
Returned in January 2009 (with a vengeance), diagnosed with pancolitis on January 30.
Currently taking Asacol (400mg 4 pills 3x daily), Rowasa nightly, Culturelle probiotic, and Zoloft (25 mg).