Hi...why is it that you cannot use mesalamine?...or is it you don't want to use mesalamine?
Lialda isn't necessarily the tops....but some do well on it, others not necessarily so. Definitely worth trying, however.
I would suggest you start at a dosage of 2400mg daily. That's 2 pills. If you need to increase, then at least you can, rather than starting at a high dosage and possibly having some symptoms that might just be mesalazine related.
If you don't want mesalazine, there's other 5ASA meds such as Colazal and Dipentum...
Regarding rectal meds...I strongly suggest you use them...the enemas would be your best bet. Of course, I'm hardcore 5ASA..so Rowasa (or maybe Pentasa is available in the US as well).
If you don't want to do 5ASA...there's steroid liquid (colocort) or steroid foam (proctofoam or cortifoam...proctofoam being of lesser amount of steroid medication)).
Where in the colon is your UC...throughout or limited?
Are you having any symptoms at this time?
*Heather* Status: mild flare enemas tapered to every 3rd night
~diagnosed January 1989 UC (proctosigmoiditis)
~UC meds: Asacol (3 x2 daily); Salofalk enemas nightly for flares & taper to maintenance
~Bentylol (dicyclomine) 20mg as needed; Ranitidine (reflux); Effexor XR 75mg(depression); Pulmicort/Airomir (asthma)
~vitamins/minerals/supplements; Probiotics....(Natural Factors Protec, Primadophilus Reuteri Pearls). @ bedtime
~various digestive enzymes as needed
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS" worth it !!!