Anyone Pregnant and on 6mp?

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Regular Member

Date Joined Feb 2009
Total Posts : 40
   Posted 5/20/2009 8:31 PM (GMT -6)   
I just spoke to my obgyn and she was concerned about the 6mp and possibility of getting pregnant. We are going to start trying when this flare ends. She read that it can cause miscarriages and fetal abnormalities. Has anyone been pregnant or heard similar things? What have others done?
Diagnosed when 13 and am now 25, female. Currently taking 100mg of 6mp, started at 60 mg of prednisone was down to 15 from slow taper and now back up to 20, and 12 pills of asacol a day. I was on cortifoam 2 times a day and am now going to start Canasa instead. I take Carafate 4 times a day for cramping and to firm up the "stuff."

Previously I've tried all types of rectal meds but nothing ever helped. In the past I've tried rowasa, enemas, pentasa, colazal, sulfasalizine. I was in a four year remission until the end of January.

Mamas Boys
Veteran Member

Date Joined Oct 2005
Total Posts : 1460
   Posted 5/21/2009 8:56 AM (GMT -6)   
My GI sent me to a maternal fetal specialist to discuss just that in a "preconception consult" so that we could evaluate the pros and cons.  We discussed Imuran (similar to 6mp) and she said that she feels comfortable with it and that it is better to remain healthy while pregnant than to flare.  She also said that if we decide to go ahead and get pregnant she would have to follow the pregnancy closely with extra ultrasounds and genetic testing to assure that the baby is developing properly.  I asked her if she felt it was not advisable to conceive under these circumstances and she said absolutely not.  As long as I was healthy I should not allow the meds to deter me from getting pregnant.  She did say though that breastfeeding was a probable no-no.  Perhaps you should get a referral to a maternal fetal specialist to discuss these issues so that you can make an informed decision.

Mamas Boys
Colazal, Azathioprine, Remicade
Culturelle, MultiVitamin, Folic Acid, Viactiv
Status: Remission!!

Veteran Member

Date Joined Feb 2009
Total Posts : 7150
   Posted 5/21/2009 9:07 AM (GMT -6)   
There's an article in the second post from the top of the page, the UC resources post, that discusses pregnancy and IBD. There is some info in it on 6MP.
Symptoms began in November 2008, ~4 weeks after giving birth to my son.
Eased for ~3 weeks in December, possibly b/c of probiotic use?
Returned in January 2009 (with a vengeance), diagnosed with pancolitis on January 30.
Currently taking Asacol (400mg 4 pills 3x daily), Rowasa nightly, Culturelle probiotic, and Zoloft (25 mg).

Mommy pooh
Regular Member

Date Joined Apr 2008
Total Posts : 131
   Posted 5/21/2009 9:09 AM (GMT -6)   
We are going to start trying for #2 as soon as this "mini flare" I'm currently having is over. I got steroid enemas yesterday that my GI said he thinks will knock this right out. He was very clear to never start trying to get pregnant while having any flare symptoms. I have read everything I can fine on 6MP and pregnancy. There are some other threads on here and in the Chrons board too. We've decided to go for it when I'm healthy again and I may knock out the next person that tells us, "it's time for #2". People can be so rude! You never know what a person is going through health wise....just don't say that.

Baby #1 was not a 6MP baby. I was in remission 2 years before and 3 months after having her with just taking Dipentum every day. The flare after having her drove me to the 6MP. Breastfeeding didn't work out with #1 so I'm not worried about trying again. Also, will be another c-section if we have another b/c #1 was breech and I don't want to risk a VBAC.
  • 26 years old, married, Stay-at-home Mommy to 2 year old daughter 
  • Ulcerative Colitis since Sept. 2004
    • 1st flare Sept-Nov 2004
    • 2nd flare Aug. 2007-July 08 
  • Currently taking:75mg 6MP, 4 Lialda, Loestrin 24, Allergy meds., Digestive Advantage Sustenex, Maxalt when I get a migraine, Zanaflex to prevent migraines, and allergy shots once a month 
  • 10/6/08 Found a 1cm kidney stone in right kidney.  Had the stone blasted and passed the fragments.


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