Certain medications are designed to target specific areas of your colon. I can't comment on the Salofalk but Asacol, depending on the PH level in your colon, can release all the way thru or half way. I am not sure what the PH level has to be but sometime if someone has left sided on down they don't do well on Asacol because the medication doesn't reach all the way. Colazal, which is a basalazide not a mesalamine, is more ideal for left sided - down. Asacol is usually the better choice for Pancolitis.
Mesalamine enemas only reach to the sigmoid colon, maybe a bit higher. But even if it only reaches so high, it can still be beneficial for someone with Pancolitis. Asacol can heal from the top on down and the enema can treat the end section.
Moderator for Allergies/Asthma and Co-moderator for UC
~Left sided Uc-'92-Colazal(9 daily),6mp(50-100mgs),Bentyl, Prilosec,Biotin,Forvia,Pro-Bio**Unable to tolerate Asacol, Rowasa or Canasa**~Year-round allergies-Singulair, Zyrtec~Secondary Reynauds Syndrome-'04-Norvasc~Sacroiliitis-epidural injections~bulging and herniated discs C5/C6 & C6/C7~3 epidural injections-second series starts 2/17, OA in my fingers -Celebrex, Tylonel Arthritis and Voltaren Gel
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