Canasa reaction

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diaper man
Regular Member


Date Joined May 2009
Total Posts : 122
   Posted 5/29/2009 12:46 PM (GMT -6)   
Has anybody had a reaction to Canasa like the big d, more bowel movements? If so did the reaction go away and did you continue to take the suppository.  I am currently having a reaction but want to see if I can get over it.
 
Thanks
Diagnosed Crohns/Colitis Jan 2007.  Allergic to 5sa. Currently taking Humira and Hydrocortisone suppositories. 
Colits in last part of Colon.  Currently bleeding every bowel movement. 


Supa
Veteran Member


Date Joined Jul 2008
Total Posts : 748
   Posted 5/29/2009 1:52 PM (GMT -6)   
I was recently on canasa (I am off of it now because the flare is under control and the canasa caused me to have severe joint pain), and it helped pretty much within the first 3 days. I did not have any increase in bowel movements, and didn't have d. Hopefully someone else will also be able to weigh on this for you with some additional information.

Good luck, and sorry to not be of more help.
Laura
 
33 years old, stay at home mom of 2 girls, ages 3.5 and 2.5
 
Diagnosed in 2007
Currently on:
Asacol 6pills/day
Biweekly injections for Humira clinical trial-going well so far!!
Canasa suppositories-1000mg nightly for recent flare


diaper man
Regular Member


Date Joined May 2009
Total Posts : 122
   Posted 5/29/2009 2:32 PM (GMT -6)   
Thanks Laura. I noticed that you are in clinical trial for Humira. I am taking that also. What are the testing in the Trial.
Diagnosed Crohns/Colitis Jan 2007.  Allergic to 5sa. Currently taking Humira and Hydrocortisone suppositories. 
Colits in last part of Colon.  Currently bleeding every bowel movement. 


Supa
Veteran Member


Date Joined Jul 2008
Total Posts : 748
   Posted 5/29/2009 2:52 PM (GMT -6)   
Well, to be honest, I am not sure what all they test for in the trial. I have a basic physical everytime I go (which levels out to be every 8 weeks, I think-right now it is every 4), and they do blood draws and urine samples everytime as well. I know they have told me before what all they test for, but for the life of me, I can't remember right now. They typically take about 4 viles of blood when I go. Oh, and I also keep a diary and have to answer questionnaires about symptoms as well as mood and other things.

So far, our trial group has responded really well. I think there has been one person who had to drop out early, but I am not sure if it was because of the Humira or for another reason.

I have been really pleased with it overall so far. I wonder how long it will take for FDA approval to come for UC though-and they never even give estimates on that!
Laura
 
34 years old, stay at home mom of 2 girls, ages almost 4 and 2.5
 
Diagnosed in 2007
Currently on:
Asacol 6pills/day
Biweekly injections for Humira clinical trial-going well so far!!
Off of canasa because of severe joint pain (side effect)


diaper man
Regular Member


Date Joined May 2009
Total Posts : 122
   Posted 5/29/2009 3:02 PM (GMT -6)   
Laura. Humira is already approved by the FDA. I saw where they have a five year registry study. Go to http://clinicaltrials.gov/ct2/results?term=humira
Diagnosed Crohns/Colitis Jan 2007.  Allergic to 5sa. Currently taking Humira and Hydrocortisone suppositories. 
Colits in last part of Colon.  Currently bleeding every bowel movement. 


saposs
Regular Member


Date Joined Nov 2008
Total Posts : 339
   Posted 5/29/2009 3:59 PM (GMT -6)   
I have been on Canasa nightly since Jan'09. The first week when i started canasa i had severe burning sensation in rectum, but it improved after a week. Though it has stopped working now despite taking double dose since May- but this is another story. I did not have any increased bowel movement with canasa. But i do feel that i am loosing hair while on canasa - maybe side effect but not sure.
Just hang in there, if your symptoms are really bad then do consult your doctor. Mine were mild though i had difficulty in sitting for a week but i was stubborn enough not to change my medicine so quick.
wish u all the best...hope canasa works for you.
Right now -FLARING (after my Rubella vaccination)
Diagnosed in Jan'2009: Canasa suppositories 1000 nightly - worked for 2 months then re-flare
13 may: canasa 1000 X2 daily for 2 weeks - to start Lialda after 2 weeks if canasa double dose does not work
Symptoms: Mucus, blood, constipated (not always), Lots Gas
Also gifted with Hypothyroid & have calicum deficiency family history!
Also started Probiotic from 23 Mar & fresh Turmeric root from 25 March'09- stopped both on 10th May


kops2da
Veteran Member


Date Joined Jun 2008
Total Posts : 2865
   Posted 5/29/2009 6:19 PM (GMT -6)   

"Allergic to 5sa. Currently taking Humira and Hydrocortisone suppositories."

Your signature says above.  So Canasa is mesalamine (5sa) and I had the same reaction with Canasa as the pills - cannot tolerate any - made everything worse.

ElaineNY 


 
Senior - New diagnosed with proctosigmoiditis - 6/2008   Tried, Colozal, steroid enemas, etc. - started working but severe side effects occurred. No mesalamines!!
Started on prednisone Feb.7, 2009 - tapering to 20 mg. - upped prenisone to 25mg. on my own (bleeding returned) - 6MP - 50 mg. 2/28/2009 - staying on 10 mg. prednisone also until visit with specialist.
 
Probiotic Align, Prilosec for GERD, Gas-X, vitamins, Calcium/D
Tylenol for knees and arthritis.
 
 
 

Post Edited (kops2da) : 5/29/2009 5:30:23 PM (GMT-6)

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