Should i start with Lialda - 2 per day or 3 per day

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saposs
Regular Member


Date Joined Nov 2008
Total Posts : 339
   Posted 5/29/2009 4:58 PM (GMT -6)   
I m stating Lialda finally after doubling canasa for 15 days failed. My GI told me if doubling canasa does not work then i should start with Lialda -dosage 3 in morning. But i have read posts where everyone normally takes 2 Lialda per day... i want to go slow. Should i also start with just 2 lialda.day instead of 3/day...and in case that does not work i will move to 3 per day.
pls advise.
Right now -FLARING (after my Rubella vaccination)
Diagnosed in Jan'2009: Canasa suppositories 1000 nightly - worked for 2 months then re-flare
13 may: canasa 1000 X2 daily for 2 weeks - to start Lialda after 2 weeks if canasa double dose does not work
Symptoms: Mucus, blood, constipated (not always), Lots Gas
Also gifted with Hypothyroid & have calicum deficiency family history!
Also started Probiotic from 23 Mar & fresh Turmeric root from 25 March'09- stopped both on 10th May


fruitgirl
Veteran Member


Date Joined Feb 2009
Total Posts : 7150
   Posted 5/29/2009 5:20 PM (GMT -6)   
I doseage of Lialda is from 2-4 per day. I guess it depends on how bad you feel! If you're feeling pretty crappy, then I'd probably go ahead and take the 3 to try to get into remission faster. You can always decrease, too, you know!
Symptoms began in November 2008, ~4 weeks after giving birth to my son.
Eased for ~3 weeks in December, possibly b/c of probiotic use?
Returned in January 2009 (with a vengeance), diagnosed with pancolitis on January 30.
Currently taking Asacol (400mg 4 pills 3x daily), Rowasa every other night, Culturelle probiotic, and Zoloft (25 mg).


saposs
Regular Member


Date Joined Nov 2008
Total Posts : 339
   Posted 5/29/2009 6:37 PM (GMT -6)   
hI fruitgirl, thanks!! I was afraid that if i start with 3 lialda per day then later my body might become used to it and 2 per day might not help later . does this happen?
Right now -FLARING (after my Rubella vaccination)
Diagnosed in Jan'2009: Canasa suppositories 1000 nightly - worked for 2 months then re-flare
13 may: canasa 1000 X2 daily for 2 weeks - to start Lialda after 2 weeks if canasa double dose does not work
Symptoms: Mucus, blood, constipated (not always), Lots Gas
Also gifted with Hypothyroid & have calicum deficiency family history!
Also started Probiotic from 23 Mar & fresh Turmeric root from 25 March'09- stopped both on 10th May


quincy
Elite Member


Date Joined May 2003
Total Posts : 30591
   Posted 5/30/2009 3:29 AM (GMT -6)   
Hi...I would start with 2...that's 2400mg, a dosage I'm on (which is 6 asacol daily). Try that for at least 2 - 4 weeks...and if it shows improvement with the 2 canasa a day..than that's good.

I would consider asking for the retention enemas rather than necessarily increasing the Lialda.

Is your Uc throughout or limited?

Keep us posted....

q
*Heather* Status: mild flare enemas tapered to every 3rd night
~diagnosed January 1989 UC (proctosigmoiditis)
~UC meds: Asacol (3 x2 daily); Salofalk enemas nightly for flares & taper to maintenance 
~Bentylol (dicyclomine) 20mg as needed; Ranitidine (reflux);  Effexor XR 75mg(depression);  Pulmicort/Airomir (asthma) 
~vitamins/minerals/supplementsProbiotics....(Natural Factors Protec, Primadophilus Reuteri Pearls). @ bedtime
~various digestive enzymes as needed
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS"  worth it !!!
 


lol?
Regular Member


Date Joined Mar 2009
Total Posts : 53
   Posted 5/30/2009 11:22 PM (GMT -6)   
I went into remission on 1 Lialda tablet per day.

notsosicklygirl
Forum Moderator


Date Joined Dec 2008
Total Posts : 16284
   Posted 5/31/2009 6:43 AM (GMT -6)   
I was taking 1200 mg Asacol 3x a day. I think that equals 3 Lialda a day. I am not sure if I would have done as well on 6 Asacol a day but there is always the option of increasing the dose. I just reduced my dose to 6 Asacol per day from 9 and so far so good.
 
I notice that my hair loss is much less on 6 compared to 9. I lost a lot of hair on the higer dose but no one has noticed. I was leaving trails of hair everywhere. It's not a big deal to me compared to constant bathroom trips.
Diagnosed with mild proctitis in March 2007: Treated with Canasa (as needed)
December 08: Began treating with Asacol 400mg (9/day) + Canasa 2x/day - Anemic
May 09: Off Canasa, taking Asacol (9/day)
Back on Canasa every other night + Asacol (9/day) + Probiotics + Iron
Reducing to 6 Asacol/day + Canasa at night + Probiotics + Iron - So far so good!!!
 


saposs
Regular Member


Date Joined Nov 2008
Total Posts : 339
   Posted 6/1/2009 3:37 PM (GMT -6)   
Thanks!
I have started with 2 per day lialda and just hoping it works.

Quincy: it's limited - is lialda o.k for that or is lialda used for throughout UC ? Also whenever i use Canasa during day, i try to retain it for atleast 6 hrs but i guess daytime canasa is giving me problem after i first empty it at around 6:00 pm.... i keep running to bathroom after that and all that comes out is brown canasa... it makes me feel even worse at night by 9:00 pm...so today i did not use the daytime canasa.... will let you know tomorrow how did it go. or do you suggest i stick to 2 per day canasa?.... i m trying your logo: "TREAT FROM BOTH ENDS " :-) Quincy, also is retention enema also mesalmine?

sicklygirl: canasa is giving me hair loss problem... i get pain at the root of hair ...i tried something i heard italians do...i took extra virgin olive oil and gave my hair little massage.... and left it for 4 hrs (rather sleep with oil on my hair - after i cover my pillow with towel).... i noticed improvement.

l0l : touchwood, happy for you ..... :-)
Right now -FLARING (after my Rubella vaccination)
Diagnosed in Jan'2009: Canasa suppositories 1000 nightly - worked for 2 months then re-flare
13 may: canasa 1000 X2 daily for 2 weeks - to start Lialda after 2 weeks if canasa double dose does not work
Symptoms: Mucus, blood, constipated (not always), Lots Gas
Also gifted with Hypothyroid & have calicum deficiency family history!
Also started Probiotic from 23 Mar & fresh Turmeric root from 25 March'09- stopped both on 10th May

Post Edited (saposs) : 6/1/2009 3:40:54 PM (GMT-6)


quincy
Elite Member


Date Joined May 2003
Total Posts : 30591
   Posted 6/2/2009 2:27 AM (GMT -6)   
Hi...yes, the lialda should be used with rectal meds..no matter how high the extent of your UC is. The point is to keep as much of your colon nice and calm and hopefully inflammation free.

Lowest dosage that works is the best....2400mg is a good dosage that's not too high. You have room to increase if you have to in the future.

When you use the Canasa at night, how much do you go in the morning?

There could be another explanation for your nightly bms....possibly food intake from the night before or what you have for breakfast even...that could increase your bms.

Remember, the colon is more active during the day, so if you're taking in a lot of some foods, they'll increase activity and have you going more often. Do you have severe urgency still?

The brown stuff would be stool and a combo of Canasa and maybe blood if you are bleeding. Nothing to worry about, however...just ucky looking.

The 5ASA retention enema is a liquid. The brand name in the US is Rowasa, as well as a generic. There are mixed reviews of the generic from various postings on our forum.

In Canada and overseas, there is Pentasa, and Salofalk enemas.

Hope you feel better soon,
quincy
*Heather* Status: mild flare enemas tapered to every 3rd night
~diagnosed January 1989 UC (proctosigmoiditis)
~UC meds: Asacol (3 x2 daily); Salofalk enemas nightly for flares & taper to maintenance 
~Bentylol (dicyclomine) 20mg as needed; Ranitidine (reflux);  Effexor XR 75mg(depression);  Pulmicort/Airomir (asthma) 
~vitamins/minerals/supplementsProbiotics....(Natural Factors Protec, Primadophilus Reuteri Pearls). @ bedtime
~various digestive enzymes as needed
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS"  worth it !!!
 


saposs
Regular Member


Date Joined Nov 2008
Total Posts : 339
   Posted 6/2/2009 12:13 PM (GMT -6)   
thanks quincy!
The canasa i use at night comes out only once with morning stools and does not trouble me and there is no urgency. The second canasa i use at around 11 a.m and retain it till 5:00 p.m mostly by trying not to get up from bed but still i start feeling the urgency from around 3:00 pm. Trouble starts at around 5:00 pm when i empty my canasa out...then there are multiple trips to bathroom. I will check if i am eating something i should not during the day.

Urgency for me is : i feel gas pressure and feel like passing gas and and instead of gas it is mucus & blood.

Update: i did not use canasa during day yesterday... i still had mucus multiple times especially towards evening.... so cansa is not the culprit so i will start using canasa during day. I think i will meet my GI after 2 weeks.
Right now -FLARING (after my Rubella vaccination)
Diagnosed in Jan'2009: Canasa suppositories 1000 nightly - worked for 2 months then re-flare
13 may: canasa 1000 X2 daily for 2 weeks - to start Lialda after 2 weeks if canasa double dose does not work
Symptoms: Mucus, blood, constipated (not always), Lots Gas
Also gifted with Hypothyroid & have calicum deficiency family history!
Also started Probiotic from 23 Mar & fresh Turmeric root from 25 March'09- stopped both on 10th May

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