Those symptoms sound very similar to my first flare. Prednisone is a mood/personality altering drug, especially if he is taking 80mg/day, so be prepared for that. I usually start out on 60mg/day, and from what I've read on here a lot of people start out on 40. I guess it could depend on your weight--I'm 150-160 lbs. For me it greatly increases my appetite. His appetite should come back with a vengeance on that much pred now that he has stopped bleeding.
27 / Male
UC Diagnosis May 2003
Survived 9 flares
Used prednisone, asacol 6/day
Alternatives: have successfully tamed 1 flare and counting without prednisone with massive doses of probiotic (along with asacol)
Diet: paleolithic (but I often cheat), non-smoker, non-drinker
Other problems: Childhood asthma