Question about Asacol

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Regular Member

Date Joined Mar 2009
Total Posts : 105
   Posted 6/26/2009 8:45 AM (GMT -6)   
I have tried Asacol the first time I was diagnosed.  The flare I was having became about 10 times worse.  My GI at the time said sometimes that happens with Asacol and moved me to Entocort.  Now my current GI suggest I give it another try as a maintenance drug.  I have been taking it for about a week.  I wasn't flaring when I started, but it seems like every day I am a little worse.  D more frequently, just hurting and miserable....but no blood.  Anyway, yesterday, I also had a couple of serious dizzy spells.  One of the times frightened me badly as I was holding my five month old grandbaby at the time and the world started to spin and go black.  Could this be from the Asacol?  Anyone have anything like this happen?  If it is a reaction to the Asacol, what are my other options for maintenance meds?
37 y/o female
non-specific colitis dx. 2007
ulcerative colits dx. 2009
diverticular disease dx. 2009
Colazal-current, but not working yet

Regular Member

Date Joined May 2009
Total Posts : 367
   Posted 6/26/2009 2:06 PM (GMT -6)   
some of the side effects you are having could be attributed to asacol. Visit the asacol website just in case but I took asacol before moving on to Lialda ... if you are taking any other medications for other conditions, even over the counter stuff, if could be reacting. You need to make a doctor's appointment soon and get a different prescription.

Elite Member

Date Joined May 2003
Total Posts : 30993
   Posted 6/26/2009 2:08 PM (GMT -6)   
yes, some people are verrrry sensitive to salicylate meds and dizziness can be a symptom.

You should also try rectal meds...maybe that will be less of side effects, or you can try the steroid topical rectal meds as well.

Since your UC is nonspecific, you're in limbo. Did the docs test you for microscopic colitis?

Your dizziness could also be caused by low iron, low b12, low vitamin D, thyroid problems, low blood sugar, etc.....
You could also have a vestibular virus or a condition called BPPV (benign paroxysmal positional vertigo)...have you seen an ENT?

It's definitely best to pursue other avenues as well....but yes, it could also be the asacol, but rather than saying it's only the asacol, try to dig a bit deeper.

Keep us posted as to how you're doing.


*Heather* Status: maintenance Asacol 6 daily + Salofalk enemas every 3rd night
~diagnosed January 1989 UC (proctosigmoiditis)
~UC meds: Asacol (3 @ 2x daily); Salofalk enemas nightly for flares & taper to maintenance 
~Bentylol (dicyclomine) 20mg as needed; Ranitidine (reflux);  Effexor XR 75mg(depression);  Pulmicort/Airomir (asthma) 
~vitamins/minerals/supplementsProbiotics....(RenewLife Ultimate Flora Critical Care + Primadophilus Reuteri). @ bedtime
~various digestive enzymes as needed
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS"  worth it !!!

Regular Member

Date Joined Apr 2009
Total Posts : 87
   Posted 6/26/2009 2:10 PM (GMT -6)   
I had an allergic reaction to Asacol. My doctors kept telling me it couldnt be the Asacol and I should keep taking it but a week later I had to be hospitailized and they determined it was an allergy to the ASAs. First I had body aches then my flare got much worse. Eventually the body aches got so bad I was unable to move my neck and arms. I would get off it ASAP if you think you could be allergic.
Currently taking: Prednisone, 6MP, VSL#3

Veteran Member

Date Joined Feb 2009
Total Posts : 735
   Posted 6/26/2009 2:20 PM (GMT -6)   
Yep Asacol gave me side effects and it made things worse after it originally helped me, as if my body could no longer tolerate it.

Regular Member

Date Joined Feb 2007
Total Posts : 385
   Posted 6/26/2009 2:50 PM (GMT -6)   
Some people are known to be allergic to 5-ASA drugs, or the Asacol isn't helping your flare
Pharmacist as of 6/12/2009.
Diagnosed 8/99. Suffered for almost 10 years. I am currently on the Specific Carbohydrate Diet and am nearing remission. I feel fantastic! I have lossed so many years to this disease.


Doc wanted to put me on 6-mp or Remicade, but I refused to take the medications! Currently on the Specific Carbohydrate Diet.  I'm in remission and life is like it always should have been.

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