I would think if you were on a higher dosage or for a very long extended period or if you are super sensitive, it could have side effects that aren't pleasant....but it is a lower dosage med and doesn't dissolve in the stomach and go through your body systemically in order to combat the inflammation, it's a topical med that's released into the ileum and colon.
It will, however, have some of the med pass through the colon wall and eventually into your bloodstream, but in a MUCH smaller amount that if you were on prednisone.
I wouldn't want to take pred, but I would consider entocort if necessary firstly.
I do hope you are using rectal meds as well....
Welcome to the forum if I haven't done so already,
*Heather* Status: maintenance Asacol 6 daily + Salofalk enemas every 3rd night
~diagnosed January 1989 UC (proctosigmoiditis)
~UC meds: Asacol (3 @ 2x daily); Salofalk enemas nightly for flares & taper to maintenance
~Bentylol (dicyclomine) 20mg as needed; Ranitidine (reflux); Effexor XR 75mg(depression); Pulmicort/Airomir (asthma)
~vitamins/minerals/supplements; Probiotics....(RenewLife Ultimate Flora Critical Care + Primadophilus Reuteri). @ bedtime
~various digestive enzymes as needed
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS" worth it !!!