Seratonin and Ulecrative Colitis

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Veteran Member

Date Joined Feb 2005
Total Posts : 1373
   Posted 7/2/2009 5:46 PM (GMT -6)   
I was curious if anyone had heard of being told to take Seratonin as an aid in treating Ulcerative Colitis.. I have a friend who's sister has U/C pretty bad and her doctor told her to start taking it.. I'm not even sure what it is.. I've heard of it, but don't know about it...
Diagnosed with U/C January 31st, 2005, IBS on July 21st, 2006 
  Status as of June 30th, 2009 :  Flaring for the last 7 or 8 months with blood, mucus PAIN..... Meds are: Prednisone 40mg daily, Lialda, 2x2 a day, Rowasa every night, Canasa every am... Xanax for stress releif and Ambien for sleep...

Regular Member

Date Joined Mar 2008
Total Posts : 113
   Posted 7/2/2009 6:16 PM (GMT -6)   
I'm thinking that's an antidepressant or anti-anxiety medication (like Zoloft, Celexa, etc.). I'm not saying it doesn't help, but it sounds like one of those docs that think UC is just stress-related and not a real disease, you know?

That being said, I do take Wellbutrin & Celexa (was on it before UC) so I don't know if I would be worse without it? I know stress surely doesn't help the disease!
Diagnosed w/ UC in August 2007
Was in remission for almost one year (using only Lialda 4xday)
Rowasa and Canasa did not work.
Current status: In Flare since May 2009

4 Lialda/day maintenance, healthy diet
Starting Colal-Pred trial May 18, 2009, ended when hospitalized two weeks later. Also diagnosed with C. Diff while in hospital.
Currently taking Vancomycin, 60mg Prednisone (start tapering soon) and doc wants to discuss MP6.

Veteran Member

Date Joined Feb 2005
Total Posts : 2103
   Posted 7/2/2009 6:19 PM (GMT -6)   
It is a neurotransmitter made by the brain and is found in animals, plants, fungi etc. It aids in a lot of functions within the body, like mood, sleep and so on.That person's  GI's logic for using serotonin to treat UC is probably coming from the fact that about 90% of serotonin in the body is found in the GI tract.
This link helps understand it a little more.

20 year old college student diagnosed in March 2005
Remission since January/April 2006-->THREE YEARS!!!!!
Trying Colazal 3 750mg x2-->Found it to be better than Asacol
25mg Elavil
75mg Effexor XR for GAD

"If you don't like something, change it. If you can't change it, change your attitude."
Maya Angelou"

Forum Moderator

Date Joined Dec 2008
Total Posts : 16728
   Posted 7/2/2009 6:48 PM (GMT -6)   
I feel like I have seen people here mention that SSRIs are bad for UC. I just looked on google and it seems like SSRIs are known to cause D and other gut problems.
Diagnosed with mild proctitis in March 2007: Treated with Canasa (as needed)
December 08: Began treating with Asacol 400mg (9/day) + Canasa 2x/day - Anemic
May 09: Off Canasa, taking Asacol (9/day)
Back on Canasa every other night + Asacol (9/day) + Probiotics + Iron
Reducing to 6 Asacol/day + Canasa + Probiotics + Iron - So far so good!!! -SPOKE TOO SOON! Back to 9/day...

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