Neither of my docs ever suspect bone loss from 5ASA, but I've not been on pentasa specifically...I've been on mesalamine for 20 years and it's never been a concern. I'm in the risk group.
I fell a few years ago injuring my shoulder..popped it out of the socket and spontaneously back in...not even a bruise..I was positive I broke my scapula or something else. nadda.
I've never been on pred, but do take a coritcosteroid inhaler for asthma (20 years at least).
I think you should consider getting your testosterone checked for sure as well as vitamin B12 and D.
I agree as well with the constant diarrhea. Have you been checked for h pylori or had an upper gastro scan done of your small intestine?
*Heather* Status: maintenance Asacol 6 daily + Salofalk enemas every 3rd night
~diagnosed January 1989 UC (proctosigmoiditis)
~UC meds: Asacol (3 @ 2x daily); Salofalk enemas nightly for flares & taper to maintenance
~Bentylol (dicyclomine) 20mg as needed; Ranitidine (reflux); Effexor XR 75mg(depression); Pulmicort/Airomir (asthma)
~vitamins/minerals/supplements; Probiotics....(RenewLife Ultimate Flora Critical Care + Primadophilus Reuteri). @ bedtime
~various digestive enzymes as needed
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS" worth it !!!