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Regular Member

Date Joined Feb 2009
Total Posts : 402
   Posted 7/3/2009 4:57 PM (GMT -6)   
Ok so I've been in touch with my IBD nurse and it looks like Methotrexate is my next option now...anyone had any experiences with this?! Any bad side effects?
I've just completely had enough of all this strong medication and I'm not sure whether I want to start taking something stronger. 
22 year old female, from the UK. Diagnosed with Ulcerative Proctitis Jan '08. Hospitalised Jan '09 for 3 days IV Hydrocortisone - had no effect! Hospitalised Feb '09 for 7 days (5 days - IV Hydrocortisone)
Currently taking daily: 
20mg Prednisolone tablets, 100mg Azathioprine (started taking 11th May),1g Acetarsol suppository, Asacol suppository (alternating nights)1g Mesalazine granules x 2 
Motilium (anti sickness), 1.5mg Zopiclone (taken when needed for sleeping), 10mg Citalopram (anti-anxiety), Probiotic Multivitamins, Nutren Build up drinks. 

Regular Member

Date Joined Sep 2008
Total Posts : 28
   Posted 7/3/2009 10:28 PM (GMT -6)   
On Monday I will give myself my 4th shot of methotrexate. I started to notice an improvement after about 3 weeks. However, I am still on a little bit of prednisone, dropped it to 15 mg today, so I won't confidently say it's working untill I'm completely off of the steroids. As for side effects, I haven't notice any really....just a little bit of a local reaction after the injection, a little burn and itchy sensation, but it doesn't last long. I'm on 25mg/ml a week, and the doctor claims this is milder than the Remicade which didn't work out so well for me.....which then made me ask why it's tried after remicade and the answer is because it's not well studied in our disease. So anyways, I'll let you know how it goes, but so far its tolerable. For myself, I think one of my biggest issues is the idea of it. I don't liek the other uses for methotrexate, being a chemo and abortion drug. I'm happy if this drug helps me feel better, but at the same time, I would like to have children one day, and I don't want to have to give myself injections for the rest of my life...
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