5ASAs while flaring?

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Regular Member

Date Joined Aug 2008
Total Posts : 95
   Posted 7/4/2009 8:12 AM (GMT -6)   
I was just wondering if any of you stop taking 5asa drugs while flaring? I remember my first real flare I had to stop taking Lialda because it just seemed to make things worse. I eventually restarted taking it and it did wonders. I'm flaring again, currently at 40mg/day of pred my GI wants me to continue to take Lialda...could there be any harm in just not taking it for a few days to see what happens?
http://asilentocean.blogspot.com/  -> My blog
Diagnosed 7/27/08
Asacol- 2.4g/day
Lialda 3.6/day
Prednisone 20mg/day 40mg/day  20mg/day and tapering again....    40mg/day and tapering again!!

Regular Member

Date Joined Jul 2009
Total Posts : 118
   Posted 7/4/2009 9:08 AM (GMT -6)   
I have never stopped taking 5asa drugs while flaring. In fact, usually they up the dose when you are flaring not stop. I found out that for me it does not make things worse.....that it is just part of the flare. My GI took me off it once because I complained of severe cramping so I could see and I got really bad and almost ended up in the hospital. When they scoped me the colitis had affected almost the whole colon when it had not started out that way. Since then I have never come of the 5asa again.

Veteran Member

Date Joined Feb 2009
Total Posts : 735
   Posted 7/4/2009 11:26 AM (GMT -6)   
Some of them drugs can make you worse. I was bleeding while on Asacol and Colazal, soon as I stopped Colazal bleeding stopped. I started taking a low dosage of Sulfasalazine after Colazal though, then eventually don't even take Sulfa that much any more. I was taking herbal things for inflammation at the same time so that is also something that could be part of it.

Veteran Member

Date Joined Mar 2007
Total Posts : 4538
   Posted 7/4/2009 11:49 AM (GMT -6)   
It shouldn't make your flare worse unless you have some type of adverse reaction to 5-ASAs which it doesn't sound like you do since you take it all the time and seem to be fine. I would never stop taking mine when in a flare.
25 years old; diagnosed March 2007;
Currently: persistent rectal inflammation
Asacol, 4 tabs, 3xday; Rowasa nightly; Viactiv; Metamucil wafers; multivitamin; Primadophilus Reuteri; sublingual allergy drops; Ortho Tri-Cyclen

Butterfly Kisses
Regular Member

Date Joined Aug 2008
Total Posts : 32
   Posted 7/4/2009 1:06 PM (GMT -6)   
I have heard Lialda has made people flare but that is a side effect of that drug so they just switched to a different ASA and it helped. You do not want to go off of your Lialda while in a flare since that is a med that is supposed to help with the inflammation. You could try switching to a different 5-ASA but I wouldn't go off. I started out on Asacol and that didn't work so I went to Colazal which has worked great for me, I tried Lialda because you don't have to take as many pills but I wasn't a fan of the side effects. I have always done better while on Colazal, in fact I started to flare when I made the dumb decision to lessen my dosage because I was feeling good. My doctor always ups my dosage while I'm flaring. My suggestion is to ALWAYS talk to your doctor before you stop taking any of your medications...I wasn't smart enough to do that the first time but I learned my lesson! Doctors usually know better than us and have thier reasons for what they tell us to take and do so we have to try to put faith in them to help us feel better.

Good luck!
26 years old...Diagnosed with Ulcerative Colitis in 2002

Currently taking: Colazal 750mg 3 pills 3x a day, Imuran 50mg 3 pills 1x a day, Remicade & B12 Injections.

Have taken: Asacol, Lialda, Entocort, Prednisone, Limotil, Nulev, Librax, Canasa & Rowasa.

potty girl
Veteran Member

Date Joined Dec 2006
Total Posts : 835
   Posted 7/5/2009 1:46 PM (GMT -6)   
Asacal and canasa is all I ever use, when I flare I just up the dose.

synthroid .088 mg, lowpressor 50 mg x 2, cozaar 25mg x2, imdur 30 mg
nitroquick, proventol, plavix 75 mg, protonix 40 mg x 2, asacal 400mg x 9
carafate 1 gm x 4, zyrtec 10 mg, rhinocort aqua nose spray, fish oil,

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