From Asacol to Lialda?

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Nor_TX
Regular Member


Date Joined Nov 2008
Total Posts : 360
   Posted 7/11/2009 11:08 AM (GMT -6)   
My GI advised me to switch from 12 Asacol per day to 4 Lialda in the mornings.  I questioned her about side effects and she said they are the same drug, but Lialda is a delayed release drug and it would stay in my colon longer.
 
Has anyone made this switch and how was it?
Presently on: 600 mg. Remicade every 4 weeks
                   Venofer infusion every 4 weeks
                   B12 every 4 weeks              
                   15 mg. Methotrexate/injection weekly
                   12 Asacol daily
                   10 mg. Celexa daily
                   Zofran as needed


quincy
Elite Member


Date Joined May 2003
Total Posts : 30705
   Posted 7/11/2009 11:19 AM (GMT -6)   
What was her reason for you to switch?

I think all you can do is try it. The dosage would be the same as what you're on of the Asacol...

quincy
*Heather* Status: maintenance Asacol 6 daily + Salofalk enemas every 4th night
~diagnosed January 1989 UC (proctosigmoiditis)
~UC meds: Asacol (3 @ 2x daily); Salofalk enemas nightly for flares & taper to maintenance 
~Bentylol (dicyclomine) 20mg as needed; Ranitidine (reflux);  Effexor XR 75mg(depression);  Pulmicort/Airomir (asthma) 
~vitamins/minerals/supplementsProbiotics....(RenewLife Ultimate Flora Critical Care + Primadophilus Reuteri). @ bedtime
~various digestive enzymes as needed
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS"  worth it !!!
 


fruitgirl
Veteran Member


Date Joined Feb 2009
Total Posts : 7150
   Posted 7/11/2009 11:58 AM (GMT -6)   
I decided to switch to Apriso (similar to Lialda in that it's a once-daily mesalamine, but is formulated to start dissolving at a lower pH) because I was having trouble remembering to take my noon dose a lot, and sometimes my evening dose. One of the biggest reasons UCers flare is because of not taking medicine as prescribed because they forget doses. So my guess is your GI is suggesting it b/c of that.
Status: Remission since late May 2009!
Symptoms began in November 2008, ~4 weeks after giving birth to my son.
Diagnosed with pancolitis on 1/30/09
Currently taking Apriso (4 pills ONCE!! daily), Rowasa twice weekly, Natural Factors Ultimate probiotic 12/12 Formula, and Zoloft (25 mg).


Nor_TX
Regular Member


Date Joined Nov 2008
Total Posts : 360
   Posted 7/11/2009 3:21 PM (GMT -6)   
No, that isn't the reason she suggested the change. She feels that because Lialda is time release, more of the medicine will stay in my colon, rather than the way Asacol does it thing in the lower intestine. She thinks that will alleviate some of the pain from inflammation.

Also, Quincy... are you familair with Lialda? Have you taken it? My GI specifically recommended a dose of 4 pills every morning, rather than the 12 I take of Asacol - 3 pills 4 times a day. I was just wondering if you were more familiar with dosages/reactions since you seem to be more specific in your advice. I've noticed that you often make specific recommendations to posts.. just wondering what your experience is.
Presently on: 600 mg. Remicade every 4 weeks
                   Venofer infusion every 4 weeks
                   B12 every 4 weeks              
                   15 mg. Methotrexate/injection weekly
                   12 Asacol daily
                   10 mg. Celexa daily
                   Zofran as needed

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