You're steroid dependent and should talk with your GI about
taking another medication to get permanently off prednisone. The next step would be Remicade. I'm not sure how long you have been on 6MP but if it's been six months and you still can't reduce your prednisone than the 6MP is not working. I'm sure I don't need to list the long term side effects of staying on even low doses of steroids.
I had this same problem; I could never get below 10mg without flaring and 6MP did not work for me. Finally the fear of long term pred use got me to seek an alternative solution.
dx proctitis in 1987
dx UC in 1991, was stable until 1998
1998 started prednisone, asacol, pentasa, nortriptylene, ativan, 6MP, rowasa enemas and suppositories, hydrocortisone enemas, tried the SCD diet, being a vegetarian, omega 3s, flax, pranic healing, yoga, acupuncture, probiotics
2000 lost all my B-12 stores and became anemic
2001 opted for j-pouch surgery- now living life med-free