Yellow Fever Vaccine

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bookgal77
Regular Member


Date Joined Jul 2009
Total Posts : 83
   Posted 7/13/2009 12:46 PM (GMT -6)   
(cross posting from CD site)
 
Has anyone here been on immunosuppressants and taken the Yellow Fever vaccine? I may need to travel to Africa for work (and maybe for fun too) in the next two years and I've gotten conflicting reports on what the vaccine can do - everything from nothing to it can be lethal (quite the range there!). I've heard it's bad to take when you're on immunosuppressants (like 6_MP) but what if you went off those for a specific time period before getting it? I'll be checking with my GI too but wanted to hear directly if anyone has gotten it or not and what happened.
**32 year old female; Diagnosed with ulcerative colitis in 2001; diagnosis changed to Crohn's disease in 2009 (but still only impacts colon)
**Asacol (4800 mg daily), 6-MP (100 mg daily), Prednisone (8 mg daily...for a few more weeks), Flagyl (250 mg every other day), Nexium (40 mg daily)
**Thankfully only two major flare-ups...2001 and 2009. Hoping to have another 8 years in between the next one (sadly, I do know there will be a next one).
**GOAL of one day being immunosuppressant free...still working on my doctor on this one but I am a world traveler who desperately wants to go to Africa one day!


Dr-A
Veteran Member


Date Joined Jul 2006
Total Posts : 2105
   Posted 7/13/2009 7:36 PM (GMT -6)   
Stamaril® must not be administered to immunosuppressed persons. If the immunosuppression is temporary, vaccination should be delayed until the immune function has recovered. In patients who have received systemic corticosteroids for 14 days or more, it is advisable to delay vaccination until at least one month after completing the course.

Live virus so it could be dangerous.

Other things you get.

Composition for 1 dose of 0.5 ml:
• The active ingredient is:
– attenuated yellow fever virus, 17 D strain, grown in chick embryos . . .. . . . . . . . . . ≥1000 U*
• The other components for the powder are stabilizer medium containing lactose, sorbitol, L-histidine hydrochloride,
L-alanine and buffer saline solution, and 0.4% sodium chloride solution for the diluent.

Remember there is no liability for any doctor if you ever have a bad side affect from any vaccine. Glad you are researching it.
Proctitis DX 1999, Pancolitis DX 2008
Golimumab study (100mg every 4 weeks)
L-Glutamine 5000 mg + 600 mg pyridoxal alpha-ketoglutarate
Probiotis/VitD3 5000IU+Ca/1000mg DHA


bettylou
Regular Member


Date Joined May 2009
Total Posts : 141
   Posted 7/14/2009 4:53 PM (GMT -6)   
I've also looked into this vaccine - am on AZA. I agree you MUST not have this vaccine - it could make you really ill since your body won't produce antibodies to fight the live vaccine. Also, I've read that you shouldn't take it until you've been off AZA/6MP for 3 months since that is how long it takes for your white blood count to return to normal levels. Sorry for the bad news... I've decided changed my travel plans because of this...
Ulcerative Colitis: diagnosed as moderate pan-colitis August 2008. Prednisolone saved me.
Current meds: Azathioprine (100mg); Asacol (too much - 6 tablets twice a day); Pentasa enemas and suppositories as needed (both great).


Anthony1977
Regular Member


Date Joined Jan 2009
Total Posts : 413
   Posted 7/14/2009 6:25 PM (GMT -6)   
This is a very interesting post .... would the same apply for Hep B vaccination or any vaccinations at that rate? I am going to become a fireman and need this vaccination.

Dr-A
Veteran Member


Date Joined Jul 2006
Total Posts : 2105
   Posted 7/14/2009 6:49 PM (GMT -6)   
Anthony1977 said...
This is a very interesting post .... would the same apply for Hep B vaccination or any vaccinations at that rate? I am going to become a fireman and need this vaccination.


Just have to pay attention to which contain live virus and which don't if you are on immunosuppressants. FLuMist, all the MMR brands, polio (orimune only), all rotavirus, smallpox, and both varicella all contain live virus. I would also choose the lesser of the "added junk" when choosing which shot to get. For example, if you have to get that Hep B go with Recombivax HB brand (Merck). It has no mercury and less added components. Both contain 250 mcg aluminum. Toxicity for aluminum is 5 mcg/kg/day. So, if you have to get more than one shot don't do more than one of the big aluminum containing vaccines at a time.

Can get a list of all components and variations here: http://www.vaccinesafety.edu/components.htm
Proctitis DX 1999, Pancolitis DX 2008
Golimumab study (100mg every 4 weeks)
L-Glutamine 5000 mg + 600 mg pyridoxal alpha-ketoglutarate
Probiotis/VitD3 5000IU+Ca/1000mg DHA


Anthony1977
Regular Member


Date Joined Jan 2009
Total Posts : 413
   Posted 7/14/2009 7:06 PM (GMT -6)   
thank you, Dr-A ... didn't mean to hijack your post bookgal.

evvie83
New Member


Date Joined Jul 2009
Total Posts : 1
   Posted 7/28/2009 5:49 PM (GMT -6)   
I went to Africa last year for 3 months, have been on Azathioprine for ten years now for Ulcerative Colitis & I was also advised not to have the yellow fever vaccine..... I was even told by one health professional that I shouldn't be going at all! needless to say, I went anyway minus the vaccine & just made sure I was pretty stringent about applying Deet mossie repellent & covering up.
 
it depends on where in Africa you are going of course, obviously I wasn't headed into some of the areas when yellow fever has a high incidence, however if there is a low risk of it in the area you are going & you are quite happy to cover yourself in repellent then you really don't have too much to worry about, just make sure you get an exemption letter from your Dr so you don't have any problems crossing borders.
 
in all honesty I was the healthiest i've ever been while travelling in Africa & I wouldn't let your disease or what meds you take hold you back! hope you get to go, its an amazing place!!
 
 
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