6mp and fatigue

New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

sweetmelody
Veteran Member


Date Joined Aug 2007
Total Posts : 650
   Posted 7/13/2009 1:41 PM (GMT -6)   
Anyone else extremely tired on this medicine? I'm at 100mg of it.. and totally exhausted with no energy? ahhh.
Kara, 22F Married.
Latest - Lialda 2 twice a day. Left Sided Colitis 40cm up...flare. Also IBS.
Medications: Lialda 2 twice a day, Align probiotic, Hyomax as needed, 6mp 50mg a day, Rowasa enemas.
I am so sick of this disease!
 
 


bookgal77
Regular Member


Date Joined Jul 2009
Total Posts : 83
   Posted 7/13/2009 2:26 PM (GMT -6)   
Yes! I'm so glad (but not really) to hear you say this...I have been taking it 4 months now, and SO tired constantly. I thought the tiredness was due to my extreme anemia, but I've been doing iron IV infusions and my blood level is normal for the first time in months, but yet I still need 10-12 hours of sleep per day to even function. I'm also on 100 mg of the 6-MP -- the main side effects I notice are fatigue, hair loss, and metallic taste in my mouth.
**32 year old female; Diagnosed with ulcerative colitis in 2001; diagnosis changed to Crohn's disease in 2009 (but still only impacts colon)
**Asacol (4800 mg daily), 6-MP (100 mg daily), Prednisone (8 mg daily...for a few more weeks), Flagyl (250 mg every other day), Nexium (40 mg daily)
**Thankfully only two major flare-ups...2001 and 2009. Hoping to have another 8 years in between the next one (sadly, I do know there will be a next one).
**GOAL of one day being immunosuppressant free...still working on my doctor on this one but I am a world traveler who desperately wants to go to Africa one day!


qwerty1
Regular Member


Date Joined Feb 2009
Total Posts : 402
   Posted 7/13/2009 2:37 PM (GMT -6)   
Yep, majorly tired alot of the time. I suffered with fatigue from the Colitis anyway before I started taking any medications but the Imuran makes it alot worse.
22 year old female, from the UK. Diagnosed with Ulcerative Proctitis Jan '08. Hospitalised Jan '09 for 3 days IV Hydrocortisone - had no effect! Hospitalised Feb '09 for 7 days (5 days - IV Hydrocortisone)
  
Currently taking daily: 
15mg Prednisolone tablets (tapering), 100mg Azathioprine (started taking 11th May),1g Acetarsol suppository, Asacol suppository (alternating nights)1g Mesalazine granules x 2 
Motilium (anti sickness), 1.5mg Zopiclone (taken when needed for sleeping), 10mg Citalopram (anti-anxiety), Probiotic Multivitamins, Nutren Build up drinks. 
                             
                             


kops2da
Veteran Member


Date Joined Jun 2008
Total Posts : 2865
   Posted 7/13/2009 2:52 PM (GMT -6)   

I took 6 MP - both 50 mg. and 75 mg. and never noticed it making me tired but always took it before bed.  Also, took prednisone at same time which gives one energy.  Right now off 6 MP (and feel MUCH better).  It did not work for my UC.  Tapering prednisone - now at 5 mg. every other day.  VERY TIRED today - hope my body adjusts soon!

ElaineNY


 
Senior - New diagnosed with proctosigmoiditis - 6/2008   
Cannot tolerate mesalamines.  New specialist (June) - Cortifoam and Anusol three times a day for now.  Hope it works!
 
Probiotic Align, Prilosec for GERD, Gas-X, vitamins, Calcium/D
Tylenol for knees and arthritis.
 
 
 


Shadam
Regular Member


Date Joined Jan 2009
Total Posts : 307
   Posted 7/13/2009 5:02 PM (GMT -6)   
I was on 100mg of 6mp but had to cut back to 50mg becuase I couldnt handle the nausea, fatigue and tiredness.

Age: 25 / Male / Florida
Diagnosed: 11/08 / Pancolitis
Diagnosed with PSC: 3/9 --now taking Urso
Asacol - 2 x 3 day (waiting for results)
6MP - 50mg - 5/04/09 - 100mg - started 6/11/09 - back to 50mg 7/8/09
Mens Multi Vitamin - 1 a day
Vitamin A Deficient - 10,000mg a day
Calcium & Vitamin D3 - 1200mc of Calcium and 800iu of Vitamin D3  
Jaro - Dophilus Probiotic (3.4 Billion) - 1 a day
 
~~~Praying for a cure~~~~
 


kops2da
Veteran Member


Date Joined Jun 2008
Total Posts : 2865
   Posted 7/13/2009 5:10 PM (GMT -6)   
Does the 50 mg. work for you? Blood tests showed that at that level it was not therapeutic so no use staying on it. Doctor said I would need to be on at least 75 or 100 mg. and I had side effects as you did!
ElaineNY
 
Senior - diagnosed with proctosigmoiditis - 6/2008   
Cannot tolerate mesalamines.  New specialist (June) - Cortifoam and Anusol three times a day for now.  Hope it works! (finding it impossible to do three times a day however)
 
Probiotic Align, Prilosec for GERD, Gas-X, vitamins, Calcium/D
Tylenol for knees and arthritis.
 
 
 


Red_34
Forum Moderator


Date Joined Apr 2004
Total Posts : 23551
   Posted 7/13/2009 5:48 PM (GMT -6)   
Yes, yes and a double yes! I am ALWAYS tired it seems. After being on 6mp for almost 3 years, I have found a way to manage my fatigue or overrule it. I found that plenty of rest, lots of water and sometimes supplementing B-12 can help counteract the fatigue.
 @--->--SHERRY--<---@
Moderator for Allergies/Asthma and Co-moderator for UC
~Left sided Uc-'92-Colazal(9 daily),6mp(50-100mgs),Bentyl, Prilosec,Biotin,Forvia,Pro-Bio**Unable to tolerate ALL mesalamines**~Allergies-Singulair, Zyrtec~Secondary Reynauds Syndrome-'04-Norvasc~Sacroiliitis~bulging and herniated discs C5/C6 & C6/C7~Epidural injections (2 series of 3), OA-Celebrex, Tylonel Arthritis and Voltaren Gel
To help Healingwell - click here: DONATE
 
 
 
 

 
 


kops2da
Veteran Member


Date Joined Jun 2008
Total Posts : 2865
   Posted 7/13/2009 6:13 PM (GMT -6)   
Good for you Red - seems everyone, nearly ,here can "handle" side effects, etc. I just can't! I would rather have a flare - although I have not had a very serious problem YET! The worst part of my UC is blood and mucous - scares me. At my worst, I had maybe 5 BM's a day - occasional diarrhea and left-sided discomfort (not really pain). But, why should I take something that makes me feel worse than UC? To each his own and of course - age does make a difference, I think!
ElaineNY
 
Senior - diagnosed with proctosigmoiditis - 6/2008   
Cannot tolerate mesalamines.  New specialist (June) - Cortifoam and Anusol three times a day for now.  Hope it works! (finding it impossible to do three times a day however)
 
Probiotic Align, Prilosec for GERD, Gas-X, vitamins, Calcium/D
Tylenol for knees and arthritis.
 
 
 


sweetmelody
Veteran Member


Date Joined Aug 2007
Total Posts : 650
   Posted 7/14/2009 7:21 AM (GMT -6)   
So tired...so so so tired.. SOOOO tired... (seriously am not thinking anything else)

Every part of my body is saying Kara, go back to sleep. I have to work with 14 to 20 month olds... i'm exhausted.

Taking the 6mp tonight for the first time because I can't do this anymore.
Kara, 22F Married.
Latest - Lialda 2 twice a day. Left Sided Colitis 40cm up...flare. Also IBS.
Medications: Lialda 2 twice a day, Align probiotic, Hyomax as needed, 6mp 50mg a day, Rowasa enemas.
I am so sick of this disease!
 
 


Red_34
Forum Moderator


Date Joined Apr 2004
Total Posts : 23551
   Posted 7/14/2009 9:50 AM (GMT -6)   
100mgs might be too much for you. Have you ever tried reducing your dosage?
 @--->--SHERRY--<---@
Moderator for Allergies/Asthma and Co-moderator for UC
~Left sided Uc-'92-Colazal(9 daily),6mp(50-100mgs),Bentyl, Prilosec,Biotin,Forvia,Pro-Bio**Unable to tolerate ALL mesalamines**~Allergies-Singulair, Zyrtec~Secondary Reynauds Syndrome-'04-Norvasc~Sacroiliitis~bulging and herniated discs C5/C6 & C6/C7~Epidural injections (2 series of 3), OA-Celebrex, Tylonel Arthritis and Voltaren Gel
To help Healingwell - click here: DONATE
 
 
 
 

 
 


sweetmelody
Veteran Member


Date Joined Aug 2007
Total Posts : 650
   Posted 7/14/2009 12:55 PM (GMT -6)   
i started at 50mg...and doc just upped my dosage on friday
Kara, 22F Married.
Latest - Lialda 2 twice a day. Left Sided Colitis 40cm up...flare. Also IBS.
Medications: Lialda 2 twice a day, Align probiotic, Hyomax as needed, 6mp 50mg a day, Rowasa enemas.
I am so sick of this disease!
 
 


bookgal77
Regular Member


Date Joined Jul 2009
Total Posts : 83
   Posted 7/14/2009 3:23 PM (GMT -6)   
I started taking the 6-MP at night based on suggestions I've read on here...while it has helped with the nasty taste it leaves in my mouth, still all I want to do is sleep, sleep, sleep. I just can't get enough sleep.
**32 year old female; Diagnosed with ulcerative colitis in 2001; diagnosis changed to Crohn's disease in 2009 (but still only impacts colon)
**Asacol (4800 mg daily), 6-MP (100 mg daily), Prednisone (8 mg daily...for a few more weeks), Flagyl (250 mg every other day), Nexium (40 mg daily)
**Thankfully only two major flare-ups...2001 and 2009. Hoping to have another 8 years in between the next one (sadly, I do know there will be a next one).
**GOAL of one day being immunosuppressant free...still working on my doctor on this one but I am a world traveler who desperately wants to go to Africa one day!


bettylou
Regular Member


Date Joined May 2009
Total Posts : 141
   Posted 7/14/2009 3:52 PM (GMT -6)   
Yes! Sooooo soooooo tired (on AZA, but its the same thing). Luckily I have a job where I can 'work from home' (i.e. sleep) a day a week to keep everything under control.

I'm trying to come off it because I've never tried to maintain remission without it so want to give it a go. I've halved my dose and am going to keep on this level for a couple of months before stopping altogether. I have probably now reached a level where the drug is ineffective at sufficiently lowering my white blood count, but the idea of not going to zero straightaway is that if I have problems it'll be quicker to get back to the full dose actually working.
Ulcerative Colitis: diagnosed as moderate pan-colitis August 2008. Prednisolone saved me.
Current meds: Azathioprine (100mg); Asacol (too much - 6 tablets twice a day); Pentasa enemas and suppositories as needed (both great).


Red_34
Forum Moderator


Date Joined Apr 2004
Total Posts : 23551
   Posted 7/14/2009 8:27 PM (GMT -6)   
Why did he increase it to 100mgs? If your fatigue is really bad, maybe you can call your doctor to see if you can lower it to 75mgs until you get used to it.
 @--->--SHERRY--<---@
Moderator for Allergies/Asthma and Co-moderator for UC
~Left sided Uc-'92-Colazal(9 daily),6mp(50-100mgs),Bentyl, Prilosec,Biotin,Forvia,Pro-Bio**Unable to tolerate ALL mesalamines**~Allergies-Singulair, Zyrtec~Secondary Reynauds Syndrome-'04-Norvasc~Sacroiliitis~bulging and herniated discs C5/C6 & C6/C7~Epidural injections (2 series of 3), OA-Celebrex, Tylonel Arthritis and Voltaren Gel
To help Healingwell - click here: DONATE
 
 
 
 

 
 


sweetmelody
Veteran Member


Date Joined Aug 2007
Total Posts : 650
   Posted 7/15/2009 7:18 AM (GMT -6)   
well i have no idea really if he's just going to drop the 6mp after i get my infusion...

he's out of the office for the week and i go on a cruise on friday.
I'm exhausted again today even though I got 8 hours of sleep

if it doesnt stop ill just do it myself
Kara, 22F Married.
Latest - Lialda 2 twice a day. Left Sided Colitis 40cm up...flare. Also IBS.
Medications: Lialda 2 twice a day, Align probiotic, Hyomax as needed, 6mp 50mg a day, Rowasa enemas.
I am so sick of this disease!
 
 


wishingitaway
New Member


Date Joined Jul 2009
Total Posts : 9
   Posted 7/16/2009 9:30 PM (GMT -6)   
On higher doses of 6mp I felt like a zombie! Between that and the anemia I could hardly function. Doc cut mine down to 25mgs and it really, really helped. No longer felt so tired and run down. I've heard folks here on the forum compare it to "flu-like" symptoms. Kind of how it was with me. But at the time I didn't realize it was actually the medication and not the disease. Now I'm really skeptical about meds! I want to know what something is before I will take it, and I don't trust Docs to give me that info - I want to research it myself.

Universal Colitis since 2003
Asacol 6 tablets per day
Mercaptopurine 1/2 tablets per day
hydrocortisone enema as needed (try not to use unless really, really needed)
Probiotic (lots!)
Fish Oil
Folic Acid (a must on 6-mp)
Iron (Solgar gentle iron - gentle on your tummy)
Multi Vitamin
Biotin
Lots of toasted french bread (especially when its actin up!)
Quiet time everyday to d-stress

kops2da
Veteran Member


Date Joined Jun 2008
Total Posts : 2865
   Posted 7/17/2009 8:16 AM (GMT -6)   

Since I found out that a blood test (Prometheus) can tell is the 6 MP at the level I was using was working, I ask about other medication.  I took 6 MP for four months hoping to feel better, etc.  It may have worked a little but blood tests showed I could not take high enough doseage to be therapeutic and no use subjecting my body to medications that won't work.

ElaineNY


 
Senior - diagnosed with proctosigmoiditis - 6/2008   
Cannot tolerate mesalamines.  New specialist (June) - Cortifoam and Anusol three times a day for now.  Hope it works! (finding it impossible to do three times a day however)
 
Probiotic Align, Prilosec for GERD, Gas-X, vitamins, Calcium/D
Tylenol for knees and arthritis.
 
 
 

New Topic Post Reply Printable Version
Forum Information
Currently it is Tuesday, June 19, 2018 8:55 AM (GMT -6)
There are a total of 2,973,181 posts in 326,066 threads.
View Active Threads


Who's Online
This forum has 160948 registered members. Please welcome our newest member, joyis.
473 Guest(s), 9 Registered Member(s) are currently online.  Details
Serenity Now, convertible68, Hardlyrob, Busted1, suttie, cppoly, fiddlecanoe, 1039smooth, straydog