I started on 50mg of 6mp on May, 4th and felt fine while on it, no side affects whatsoever. My blood tests came back perfect so my GI jumped my dosage up to 100mg and thats when the side affects hit me (they hit me hard). I had sever nausea, fatigue, tiredness, dizinees, etc... the side affects were so bad that I had to take 2 days off of work. My 2nd month blood tests came back un satisfactory so my doc reduce my doasage back down to 50mg, he might raise them to 75 soon however.
In regards to when you should take them, I would do it right before you go to bed only becasue the main side affect is fatigue and tiredness.
Good luck and make sure you get your blood tests done!
Age: 25 / Male / Florida
Diagnosed: 11/08 / Pancolitis
Diagnosed with PSC: 3/9 --now taking Urso
Asacol - 2 x 3 day (waiting for results)
6MP - 50mg - 5/04/09 - 100mg - started 6/11/09 - back to 50mg 7/8/09
Mens Multi Vitamin - 1 a day
Vitamin A Deficient - 10,000mg a day
Calcium & Vitamin D3 - 1200mc of Calcium and 800iu of Vitamin D3
Jaro - Dophilus Probiotic (3.4 Billion) - 1 a day
~~~Praying for a cure~~~~