Tape Worms to treat IBD (article)

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pb4
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   Posted 7/14/2009 12:39 PM (GMT -6)   
 
 
:)
My bum is broken....there's a big crack down the middle of it! LOL :)


seconder
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   Posted 7/14/2009 3:43 PM (GMT -6)   
Tapeworms are a little scary in that they are segmented and the segments can break off and migrate to other parts of the body where they can do damage.  I wouldn't want a tape worm lodged in my liver.

pb4
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   Posted 7/14/2009 6:17 PM (GMT -6)   
I believe this is a different species of tape worm, they have no teeth and the Dr. being interviewed mentioned some other things as well (which I cannot remember) but bottom line he said they would be safe, however they are looking to incorporate what they learn from these tape worms for a less gross way of treatment.
 
As stated in the article "The one we use is a tape worm with no hooks, no teeth. It does no actual damage to the intestine."   So it's likely that it's safe on all counts, in the small study that was done there were no issues mentioned with segments in the liver or any other issues.

:)


My bum is broken....there's a big crack down the middle of it! LOL :)


seconder
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Date Joined Jun 2008
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   Posted 7/14/2009 8:38 PM (GMT -6)   
I don't think it has to do with teeth. I seem to remember that tapeworms are like a string of sausage links. Each of those links can break off to migrate and, if I'm not mistaken, regenerate another tapeworm. Sometimes they migrate to the liver (and lungs?) In an otherwise healthy person, that may not be a problem. Given the higher incidence of liver problems in people with uc, I'd be wary to ingest a worm that might migrate there.

Probiotic
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Date Joined Mar 2007
Total Posts : 2832
   Posted 7/15/2009 9:04 AM (GMT -6)   
Interesting. One of the two enterpreneurs who are providing helminthic (worm) therapy do offer tapeworm, I believe primarily for asthma. The same guy offers hookworm as does another vendor, who also offers human whipworm. Tapeworm, like hookworm and whipworm are extremely common in the developing world and infect billions. I don't know how symptomatic a low dose of tapeworm is- I know that most people in developing countries with hook and whipworm suffer no symptoms at all unless they have very high worm burdens. I was not aware of the migration issue for tapeworm- anyway you and I have enough to handle integrating- or trying to- whipworm into our immune systems but it's good to see worm research for auto-immune conditions keep expanding.
Pancolitis >20 years, allergic to all 5ASAs
(To pharma: enough already with the umpteen variants of Asacol!)
Tried everything under the sun (natural and alternative), low carb SCD
Some partial success with TSO but  too expensive to keep up 
Remicade Humira, lots of probiotics, entocort, tapering increasing pred again,
homemade fecal infusions, maybe surgery this year soon
 
 


Eva Lou
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Date Joined Sep 2006
Total Posts : 3442
   Posted 7/15/2009 11:13 AM (GMT -6)   
I just can't deal with the gross factor.... worm burdens?!?!?!! Uugghhhh...... The thought of deliberately ingesting them just grosses me out to the max. Much more so than deliberately injecting mouse proteins into me! I'm sure it does help, the worm therapy, but it's no cure. For anything, asthma, UC, etc. so it's just supposed to alleviate the symptoms to the point where your life isn't affected by them? And, for you 2 taking the worms- have you noticed any change from your "regular" bathroom habits? Seconder, I know you posted that you were doing ok, mornings being the worst- this is me on a "normal" day! So have things improved at all from say a month ago? Or changed at all?
diagnosed with UC '02
meds-
Asacol- 8 tabs/day
Remicade-10mgs/kg- since 4/07
Imuran- 150mgs/day
various probiotics
Fiber supplement
 
 
 


Probiotic
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Date Joined Mar 2007
Total Posts : 2832
   Posted 7/15/2009 1:32 PM (GMT -6)   
Looking at this link a second time, esp. the video, I see that the only application of tapeworms for colitis by this researcher has been in "model" systems i.e. mice induced to have colitis, not humans, while the studies they refer to in humans are the well established studies with microscopic pig whipworm eggs. Also, the video byte is rather behind the times, though, by refering to the TSO studies as still "small" and "preliminary" when in fact they moved on years ago to much larger double-blind peer-reviewed and published UC and Crohn's studies with hundreds of patients, and by now many thousands have been subsequently treated.

As far as symptoms with the worms.... well, when I took TSO for a couple years I never had any side effects at all. (Contrast this to 5ASA drugs which gave me the worst pain and D I have ever experienced- worse even than my most horrible flare days.) This may not be true for whipworm and is certainly not true for hookworm. There may be an adjustment phase of several months or longer beginning when they themselves embed themselves in the gut tissue. My goal is to see if this will save my colon. If I fail, no harm done really as these are very common parasites that infect billions- most without symptoms. As far as the gross factor, I find it more gross that we are missing something - be it probiotic bacteria, or parasites, that were natural to man all the way back to our earliest ancestors. Our colons- healthy or not- have far, far more bacterial cells present than there are other cells in the whole body.

TSO helped me- no doubt about it- but alot hinges on whether human whipworm will be more potent, as I am looking for total remission not dampening. If it is only as good as TSO, then for me it will still mean colon removal. But we'll just have to wait and see for at least a few months to even know if it will be beneficial. There is at least one individual who did get into a three year plus remission on them- and from which the interest was derived- I will try and dig up the video link again.


Pancolitis >20 years, allergic to all 5ASAs
(To pharma: enough already with the umpteen variants of Asacol!)
Tried everything under the sun (natural and alternative), low carb SCD
Some partial success with TSO but  too expensive to keep up 
Remicade Humira, lots of probiotics, entocort, tapering increasing pred again,
homemade fecal infusions, maybe surgery this year soon
 
 


pb4
Elite Member


Date Joined Feb 2004
Total Posts : 20577
   Posted 7/15/2009 4:44 PM (GMT -6)   
I didn't veiw the video ( I saw the story on the news and went to the news site so I could share the story here), but maybe the video on the link was pertaining to past studies regarding worm therapies cuz from my understanding this particular story is about a recent study doen on a small group of colitis patients where they added the tape worm eggs into gatoraid for them to consume in order to see what the results would be specifically with the tape worm.

:)
My bum is broken....there's a big crack down the middle of it! LOL :)


Probiotic
Veteran Member


Date Joined Mar 2007
Total Posts : 2832
   Posted 7/15/2009 5:08 PM (GMT -6)   
Well, the quote "[a] small American study showed that when people with colitis were given a dose of microscopic worm eggs in Gatorade, they noticed an improvement, but it was a preliminary study," to me indicates that the reference is to the earliest, tiny TSO trial (the one with less than ten patients). The study was since expanded into large studies with hundreds of patients, but the tapeworm researcher in the article is Canadian and since the reference is to an American study, it sounds like the tapeworm idea is still in preliminary research with mouse models. The article (newsbyte) is very poorly written.
Pancolitis >20 years, allergic to all 5ASAs
(To pharma: enough already with the umpteen variants of Asacol!)
Tried everything under the sun (natural and alternative), low carb SCD
Some partial success with TSO but  too expensive to keep up 
Remicade Humira, lots of probiotics, entocort, tapering increasing pred again,
homemade fecal infusions, maybe surgery this year soon
 
 


pb4
Elite Member


Date Joined Feb 2004
Total Posts : 20577
   Posted 7/15/2009 5:54 PM (GMT -6)   
On the news yesterday when I was watching, they talked to the GI doing this study (with the tape worms) and he said specifically they put tape worm eggs into gatoraid, maybe a confusion in what they wrote in the article compared to what was said by the GI...agree, the article is poorly done since it doesn't reflect word for word what the GI on the news being interveiwed said.

:)
My bum is broken....there's a big crack down the middle of it! LOL :)

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