I agree with Sherry. I used it every night for 3-ish months, then started tapering and am now doing it twice weekly. But, I have pancolitis, so am also on Apriso. If I find that I need to use Rowasa more often to stay in remission for long periods of time, I will. There's nothing to be scared of...it's perfectly safe for nightly use as a maintenance.
Status: Remission since late May 2009!
Symptoms began in November 2008, ~4 weeks after giving birth to my son.
Diagnosed with pancolitis on 1/30/09
Currently taking Apriso (4 pills ONCE!! daily), Rowasa twice weekly, Natural Factors Ultimate probiotic 12/12 Formula, and Zoloft (25 mg).