Some of the side effects can be exacerbation of symptoms. I believe that some doctors prescribe the highest dosage and the patient cannot tolerate that amount.
Best to start lower and increase in incriments.
It's a treatment medication as well as maintenance. The use of oral and rectal is optimum.
I started with 20 times a day...explosive, razor-like bloody diarrhea....the only meds I've used is the 5ASA oral/rectal.
Not all patients can use all meds...there are some who cannot use the 5ASA meds at all.
*Heather* Status: maintenance Asacol 6 daily + Salofalk enemas every 4th night
~diagnosed January 1989 UC (proctosigmoiditis)
~UC meds: Asacol (3 @ 2x daily); Salofalk enemas nightly for flares & taper to maintenance
~Bentylol (dicyclomine) 20mg as needed; Ranitidine (reflux); Effexor XR 75mg(depression); Pulmicort/Airomir (asthma)
~vitamins/minerals/supplements; Probiotics....(RenewLife Ultimate Flora Critical Care + Primadophilus Reuteri). @ bedtime
~various digestive enzymes as needed
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS" worth it !!!