Align vs. VSL#3

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Regular Member

Date Joined May 2009
Total Posts : 227
   Posted 7/29/2009 1:39 AM (GMT -6)   
Has anyone tried VSL#3 or Align probiotics?  Has either one helped you/what were your experiences?  If anyone has tried both, which one worked better?  I am just wondering because currently I am on VSL#3, and considering trying Align instead to see if it works better.  Any info would be appreciated!
UC since 1994
4 Lialda/day, 15 mg prednisone and tapering (down from 40 mg), rowasa, folic acid, VSL#3, flax oil, vegetarian diet

Veteran Member

Date Joined Mar 2008
Total Posts : 678
   Posted 7/29/2009 7:06 AM (GMT -6)   
I have tried both. I like Align better.
32 yr old female
Mild Pancolitis
UC since 2000 - in remission for most of those 8 years med free.
Cannot tolerate mesalamine. Currently take probiotics and fish oil. Trying Applied Kinesiology & supplements.

Rio in Maryland
Veteran Member

Date Joined Nov 2007
Total Posts : 891
   Posted 7/29/2009 9:12 AM (GMT -6)   
I'm using VSL#3 and it seems to be working fine. I've never tried Align but a number of people here seem to be happy with it.

AMK77, just wondering, why do you prefer Align to VSL#3? More effective? Fewer side-effects (like bloating)?

The only problem I have with VSL#3 is the price. It's probably one of the most expensive probiotics on the market.
Rio, 33 year old male. Diagnosed with UC in 2006
Azathioprine (stopped), 4800 mg Asacol
VSL#3, Metamucil
Vitamin E enema or Canasa/Mesacol suppository occasionally

Veteran Member

Date Joined Jul 2008
Total Posts : 748
   Posted 7/29/2009 10:47 AM (GMT -6)   
I have not tried VSL#3, but would like to.  Align did not work for me-it made me feel worse.  However, I seem to be the exception because even my GI was surprised and said she tells a lot of patients to use it.
Worth a try!! 
34 years old, stay at home mom of 2 girls, ages 4 and 2.5
Diagnosed in 2007
Currently on:
Asacol 6pills/day
Biweekly injections for Humira clinical trial-going well so far!!
Back on Canasa temporarily because I took Biaxin for sinuses and started seeing streaks of blood again.
Also take multivitamins and milk thistle daily.

Regular Member

Date Joined Feb 2009
Total Posts : 226
   Posted 7/29/2009 2:16 PM (GMT -6)   
I've tried VSL#3, Align, and many other "high quality" probiotics. I've found Culturelle to be the best for me, and it's WAY cheaper than VSL#3.
33 year old male
diagnosed severe pancolitis in 2004, unresponsive to all drugs
turned down recommendation to have j-pouch surgery
have been mostly symptom free since 2004 via diet modification (removed all carbs)

Veteran Member

Date Joined Mar 2008
Total Posts : 2855
   Posted 7/29/2009 2:48 PM (GMT -6)   
I tried Align but it always gave me a stomach ache.
And the refrigerated probiotics are better.
49 year old female attorney, diagnosed UC/pancolitis 1985, no surgery but much suffering. Asacol maintenance for 20+ years; used prednisone & Rowasa for flares.  Probiotics (Ultimate Flora, 50 billion), salmon oil (omega-3) when I can remember. 
August 2008 sought care of naturopathic doctor. Food sensitivity test showed wheat/gluten, other intolerances; eliminated wheat/gluten from my diet.
Bad flare in March, used prednisone. Humira denied, started Remicade 4/12 and doing great~ learning what normal is~ wow

Regular Member

Date Joined Sep 2008
Total Posts : 211
   Posted 7/30/2009 8:52 AM (GMT -6)   
I use Align and it seems to work ok for me.

36/f   proud single mom of 2

Diagnosed with GERD/Acid Reflex 2002

Diagnosed with IBS 2007

Diagnosed with Arthritis 2007

Diagnosed with UC, then Crohn’s 2008, now the GI isn't sure which is it exactly...he calls me a strange case.

Diagnosed with Generalized Anxiety Disorder 2008

Current medications: Asacol 2 tablets 3X daily, Imuran 50 mg daily,Endcort 3mg 2X daily, Pentasa 2 500mg caps 2X daily, Prilosec 20 mg 2X daily (if needed), Cymbalta 60 mg daily. 05 mg Zanax (if needed) Probiotics, Calcuim/Mag/Vit.D. Flinstones multi with Iron and Vit. C 500mg daily

Regular Member

Date Joined Oct 2008
Total Posts : 192
   Posted 7/30/2009 5:27 PM (GMT -6)   
I also take Align and it is working for me. I take since almost a year.
It is not true that refrigerated probiotics are better, if that were so, why? I tried refrigerated probiotics and they send me back to the crapper with lots of cramps. I tried them three times. So, they are NOT better - maybe they just work better for you PERSONALLY. As a matter of fact, they are very expensive and there is no guarantee that they work as I personally have seen it.
You just have to give it a try and see what happens.
Scarlett, 38 yo., TX
Pancolitis since 3/1997
6 x Asacol a day
75 50 mg 6-MP
Align (probiotic)
Flintstones Complete Vitamins
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