Red Rash on face - 6MP or Prednisone reaction?

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Regular Member

Date Joined Mar 2008
Total Posts : 113
   Posted 8/3/2009 10:49 AM (GMT -6)   
I have developed an itchy, burning red rash on both of my cheeks. I started 50mg of 6MP last Thursday and am tapering the Pred (down to 2.5mg every other day). I left a mssg for my GI, but was wondering if any of you had a similar reaction from either drug?
Diagnosed w/ UC in August 2007
Was in remission for almost one year (using only Lialda 4xday)
Rowasa and Canasa did not work.
Current status: In Remission since June 2009

4 Lialda/day maintenance, healthy diet
Starting Colal-Pred trial May 18, 2009, ended when hospitalized two weeks later. Also diagnosed with C. Diff while in hospital.
Currently taking 20mg Prednisone (tapering).

Veteran Member

Date Joined Feb 2009
Total Posts : 7150
   Posted 8/3/2009 10:54 AM (GMT -6)   
I'd be more likely to suspect 6MP, since it sounds like you've been on the pred for a while. Of course, I know some people get odd reactions when they taper pred, so that might be it as well.

Have you changed your cleaner, shampoo, laundry detergent, etc lately?
Status: Remission since late May 2009!
Symptoms began in November 2008, ~4 weeks after giving birth to my son.
Diagnosed with pancolitis on 1/30/09
Currently taking Apriso (4 pills ONCE!! daily), Rowasa twice weekly, Natural Factors Ultimate probiotic 12/12 Formula, and Zoloft (25 mg).

Veteran Member

Date Joined Jul 2009
Total Posts : 526
   Posted 8/3/2009 12:39 PM (GMT -6)   
I've had rosacea for a number of years now, and when I last saw my GP she asked me if steroids helped, and that pred is sometimes prescribed for rosacea.

I told her I hadn’t made a connection, but when I recently started an entocort regimen, I took note. It did indeed help, and my rosacea is currently in complete remission. Wish I could say the same for my UC!
[CENTER]First Diagnosed Feb 2007
Significant flare June-July '07 treated with Prednisone
Asocol X 6 per day
Largely in remission with some minor flares treated with Entocort

Regular Member

Date Joined Feb 2009
Total Posts : 226
   Posted 8/3/2009 1:09 PM (GMT -6)   
When I was on prednisone (years ago), I had rashes on my face and back ... but as I tapered it went away.
33 year old male
diagnosed severe pancolitis in 2004, unresponsive to all drugs
turned down recommendation to have j-pouch surgery
have been mostly symptom free since 2004 via diet modification (removed all carbs)

Regular Member

Date Joined Oct 2008
Total Posts : 192
   Posted 8/3/2009 4:32 PM (GMT -6)   
I had the red rash that you describe almost immediately when I started 6MP. The rash went away, but since then I have acne/very bumpy skin/zits around my chin and jaw line. Using Noxema products has helped me and still does.
Scarlett, 38 yo., TX
Pancolitis since 3/1997
6 x Asacol a day
75 50 mg 6-MP
Align (probiotic)
Flintstones Complete Vitamins

Elite Member

Date Joined Apr 2004
Total Posts : 23551
   Posted 8/4/2009 7:01 AM (GMT -6)   
I'm not on pred but I started developing a rash around my mouth, chin and under my nose approximately 1 1/2 years after being on 6mp. I had to get it under control with topical steroids and then I am now containing it with Elidel. If I don't use the Elidel, it comes back and my GP thinks it is from the 6mp. 6mp, if you look at the side effects, can cause rashes.

Moderator for Allergies/Asthma and Co-moderator for UC
~Left sided Uc-'92-Colazal(9 daily),6mp(50-100mgs),Bentyl, Prilosec,Biotin,Forvia,Pro-Bio**Unable to tolerate ALL mesalamines**~Allergies-Singulair, Zyrtec~Secondary Reynauds Syndrome-'04-Norvasc~Sacroiliitis~bulging and herniated discs C5/C6 & C6/C7~Epidural injections (2 series of 3), OA-Celebrex, Tylonel Arthritis and Voltaren Gel
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