Hi. Yes, Canasa isn't for everyone. It makes me feel worse too. I can sometimes deal with Rowasa (mesalamine enemas) but generally they are also not great for me. As Thatfield said, the Cortenema is not the same as taking pred, so I wouldn't worry too much. Generally, when I'm in bad shape, my doctor has me use Cortenema for a couple weeks, taper, then switch to Cortifoam. You can pretty much use Cortifoam long-term without problems since the steroid absorption is minimal. My doc has told me that and someone else here with a big doc at UNC-Chapel Hill (I think) confirmed it too.
UC for the last ten years
Current Meds: 6MP since 2006, Lialda, Asacol foam, Lomotil
Past Meds: You name it; I've tried it. (Asacol, Colazol, Pentasa, DiPentum, Rowasa, Canasa, Cortenema, sulfasalazine, Cortifoam)
Alternative treatments I have had success with: Acupuncture, Hypnotherapy