Low dose naltrexone (LDN)

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Regular Member

Date Joined Aug 2009
Total Posts : 198
   Posted 8/10/2009 5:38 PM (GMT -6)   
Does anyone know anything about LDN and it's results for colitis patients? I haven't found much on the web besides the fact that Penn State applied for and was granted funds (via NIH) to have some further clinical trials.
Lialda 4x a day
Rowasa Enema 1x at night
Align (Probiotic) 1x a day
Fish Oil 4x a day
Multi-Vitamins (includes Vitamin D, Vitamin C) 1x a day

Forum Moderator

Date Joined Dec 2008
Total Posts : 15922
   Posted 8/10/2009 8:12 PM (GMT -6)   
Some people here have tried it and have had mixed results. I think glamourgirl and miracles both tried it and neither had much of an improvement if I remember correctly. I hope you get some responses.
Diagnosed with mild proctitis in March 2007: Treated with Canasa (as needed)
December 08: Began treating with Asacol 400mg (9/day) + Canasa 2x/day - Anemic
May 09: Off Canasa, taking Asacol (9/day)
Back on Canasa every other night + Asacol (9/day) + Probiotics + Iron
Reducing to 6 Asacol/day + Canasa + Probiotics + Iron - So far so good!!! -SPOKE TOO SOON! Back to 9/day...

Veteran Member

Date Joined Dec 2006
Total Posts : 517
   Posted 8/11/2009 5:22 AM (GMT -6)   
I've been on LDN for about 6 months now and my UC symptoms are somewhat better.  I seem to have more energy and I'm able to eat more like a regular person.  It hasn't been the miracle that I was hoping for though.  I had really good results the first couple of months after I started LDN...but like everything else I've tried (different diets, supplements, and meds), the good results seem to taper off.  I'm adjusting my dosage to see if I can recapture the results I had early on.
36 y.o. male
Diagnosed w/ UC in May '06, had symptoms since '99
Meds & supplements: LDN 4.5mg, Florastor, Lialda, Allegra, multi-vitamin, buproprion, fluoxetine, vit E, D, and zinc.
Eating a low sugar and wheat, and no dairy diet.

New Member

Date Joined Jun 2009
Total Posts : 10
   Posted 8/11/2009 10:24 AM (GMT -6)   
i tried LDN about a year ago and it did nothing for me!

Regular Member

Date Joined May 2009
Total Posts : 25
   Posted 8/11/2009 11:23 AM (GMT -6)   
It makes me a bit skeptical when I read that Naltrexone can/ may help with so many different things. That sends a red flag up for me. Either it's truly the miracle drug or overated. I may talk with my doc about it though.

Regular Member

Date Joined May 2009
Total Posts : 25
   Posted 8/11/2009 11:25 AM (GMT -6)   
Oh, just in case anyone wants to read up some more on it.

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