Hi..you should be on both oral and rectal meds...oral to take care of the cecal patch (Pentasa does dissolve in the terminal ileum and will hit the patch nicely methinks) Asacol does as well, but not all have it dissolving in their colons. It's worth a try with that firstly, however.
The retention enemas will hit all the rectum and the sigmoid...for yours may be limited now, but there's still a chance it can spread upward.
The enemas also have 2g or 4g medication dosages.....more bang for the buck...
I base that on my 20 years experience of using only oral/rectal 5ASA meds...and my UC has never been as bad as the first year. A good track record and my c-scopes say it works as well.
Low in the rectum inflammation is difficult to treat because even with suppositories or the enemas concentrated in just the rectum...it's the most stubborn area.
Hope you feel better soon....
*Heather* Status: ...Asacol 3 twice daily; Salofalk enemas every 2nd night
~diagnosed January 1989 UC (proctosigmoiditis)
~UC meds: Asacol (3 @ 2x daily); Salofalk enemas nightly for flares & taper to maintenance
~Bentylol (dicyclomine) 20mg as needed; Ranitidine (reflux); Effexor XR 75mg(depression); Pulmicort/Airomir (asthma)
~vitamins/minerals/supplements; Probiotics....(RenewLife Ultimate Flora Critical Care + Primadophilus Reuteri). @ bedtime
~various digestive enzymes as needed
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS" worth it !!!