6MP also put me into remission from the third week that I took it - initially 75 mg a day. That would be 1 1/2 pills a day. I am now at 50 mg, because the side effects were too bad.
PROS: Puts me in remission; only 1 pill in the evening (I take 4 Asacol/day additionally as a cushion), makes me tired and therefore I sleep well, seems to keep me out of flares (haven't flared in 8 months, I use to flare every 3 months for at least 6 weeks).
CONS: Constantly tired, initial hair loss, initial headaches for days at times, initial nausea for weeks, body aches, no apetite, considerable weight loss, have to be monitored periodically by having blood work monthly (in the beginning it is weekly, then biweekly, then monthly - depends on the doc), can't drink alcohol when on 6MP (I don't drink, but if you do, you might want to consider it), sensitive gums and teeth, acne or at least several fat zits at the same time, dry skin, sometimes feeling shaky, sometimes dizziness. 6MP can considerably decrease the amount of the white and red blood cells, inhibits blood clotting and cause inflamation of the liver and pancreas and liver failure. Just to mention that.
Well, these are my PROS and CONS. I am willing to take all the cons just for the fact that I am not flaring. I can deal with the cons much better than with the constant loo trips, pain, bleeding, urgency, totally sick feeling ways of a flare and not being able to go somewhere or meet people.
But you have to decide for yourself.
Might sound very dark, but I don't worry about risks from 6MP anymore. I want to feel better NOW, I tried long enough just to stay only on "less harmless" meds like Asacol and enema and when i hit rock bottom, i took Pred and it didn't even work for me.
Please don't take it the wrong way and don't take it personally, i am not implying anything about the severity of your condition, but some people including me only realize how severe and torturing their condition is when they suffer for a long long time, because they are too scared to try something new, something controversial or something "risky".
I started taking 6MP out of total despair. I am scared of Remicade and Humira, but if the day ever comes that I have to give it a try, I certainly will first resist and throw a tantrum until I feel so poor and horrible that I am begging to try it out.
Best of luck and great that you are making an informed decision.
Scarlett, 38 yo., TX
Pancolitis since 3/1997
6 x Asacol a day
75 50 mg 6-MP
Flintstones Complete Vitamins