Colazal generic question

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New Member

Date Joined Aug 2009
Total Posts : 3
   Posted 8/12/2009 1:50 PM (GMT -6)   
Hi i took the generic for colazal 3 hours ago, i took 3 pills at once, and now i have really bright yellow urine and bright yellow in my bowel movments.
Currently i have had the runs for 2 weeks straight, not being able to leave the house, and extreme stomach pain. I am 19 years old and do not Have any medical insurance and cannot afford to go to any doctors. I just found a bottle of the generic that i had not finished, it does nto expire till december, so i dont think it has to do with being old or anythign like that. i think i remember this happeneing a few times when i was on it earlier in the year, is this normal?
Does it mean that i am not absorbing the medicine?
Or does this mean something else is wrong??
I am so confused and frustrated.

Rio in Maryland
Veteran Member

Date Joined Nov 2007
Total Posts : 891
   Posted 8/12/2009 2:34 PM (GMT -6)   
I know some people have had problems with generic colazal and had to switch back to the original brand.

What other meds are you on?

Colazal's typically taken as a maintenance drug even when you're in remission, but it seems you're taking colazal only when you have a flare. Is that right? If you're only starting back on it now then maybe it will take a few days for your body to get used to it.
Rio, 33 year old male. Diagnosed with UC in 2006
Azathioprine (stopped), 4800 mg Asacol
VSL#3, Metamucil
Vitamin E enema or Canasa/Mesacol suppository occasionally

Regular Member

Date Joined Jul 2009
Total Posts : 321
   Posted 8/12/2009 3:06 PM (GMT -6)   
I always have yellow in my stool when I am on colazal. I am not sure about the urine as i have not noticed a change in color. Are you drinking enough water and staying well hydrated?
UC since 2002- remission for 6 years
recent flare 06/09
Currently on Colazal, multivitamin, probiotics, fish oil
just tapered off prednisone

New Member

Date Joined Aug 2009
Total Posts : 3
   Posted 8/12/2009 6:32 PM (GMT -6)   
i am not on any other drugs except birth control and and allergy pill everyday because i also get hives pretty badly.

Forum Moderator

Date Joined Apr 2004
Total Posts : 23551
   Posted 8/12/2009 7:03 PM (GMT -6)   
If I don't drink enough water, my urine turns a bright yellow (think neon) and it wasn't like that before I started on Colazal. So I think you may need to increase your fluid intake. I sometimes too have yellow stool but keep an eye on that and mention it to your doctor if it continues because it can also indicate liver issues.
Moderator for Allergies/Asthma and Co-moderator for UC
~Left sided Uc-'92-Colazal(9 daily),6mp(50-100mgs),Bentyl, Prilosec,Biotin,Forvia,Pro-Bio**Unable to tolerate ALL mesalamines**~Allergies-Singulair, Zyrtec~Secondary Reynauds Syndrome-'04-Norvasc~Sacroiliitis~bulging and herniated discs C5/C6 & C6/C7~Epidural injections (2 series of 3), OA-Celebrex, Tylonel Arthritis and Voltaren Gel
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Old Hat
Veteran Member

Date Joined Feb 2007
Total Posts : 5154
   Posted 8/12/2009 9:05 PM (GMT -6)   
It's typical of Colazal to have bright yellow urine-- especially 2-3 hrs after you've taken a dose. Like Sherry says, drink plenty of water throughout the day while you're on it. Original Colazal was my best 5-ASA med ever, but I had to go on the generic a yr ago due to insurance requirements. The generic (made by Watson Pharma) gave me severe headaches-- so I went back to brandname Colazal. I think it has been altered recently by Salix; it still seems to have good anti-inflammatory properties but doesn't control D like it used to-- when it also caused dry mouth. In your situation it should be better than nothing-- you'll know whether it's helping in a week or two. It would take a few months to subdue a moderate flare, though, judging from personal experience & what my gastro says about it. If you have pancolitis, you might do better on something else. / Old Hat (30 yrs with left-sided UC ... [etc.])
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