I think Nutz and Meesh make some good points. Pred is not a maintenance drug; if you have been on pred for more than 4 months you are prednisone dependent. If the immunosuppressants and biologics have failed you have reached the end of treatment options. I also know it's hard to wrap your mind around surgery so while you and your GI work out the next plan it would be good for you to get a surgical consultation. Meeting with a surgeon does not commit you to surgery but educates you about the process in the event you ever have to choose it.
I chose surgery because I was steroid dependent and came to the decision that I was never going to gain remission. That was 8 years ago and I have never regretted it.
dx proctitis in 1987
dx UC in 1991, was stable until 1998
1998 started prednisone, asacol, pentasa, nortriptylene, ativan, 6MP, rowasa enemas and suppositories, hydrocortisone enemas, tried the SCD diet, being a vegetarian, omega 3s, flax, pranic healing, yoga, acupuncture, probiotics
2000 lost all my B-12 stores and became anemic
2001 opted for j-pouch surgery- now living life med-free