Hi..welcome to the forum!
I don't have any experience with the pred or 6MP, but I can truly understand the fears of possible outcomes regarding meds and surgery.
t seems your situation is complicated and hopefully others who have more experience will offer some input.
Is your UC throughout your colon or limited?
Have you tried any of the rectal medications at all in combination with the ASacol and others?
I hope you have good support at home through family and friends to help you emotionally as well as physically, etc.
*Heather* Status: ...Asacol 3 twice daily; Salofalk enemas every 2nd night
~diagnosed January 1989 UC (proctosigmoiditis)
~UC meds: Asacol (3 @ 2x daily); Salofalk enemas nightly for flares & taper to maintenance
~Bentylol (dicyclomine) 20mg as needed; Ranitidine (reflux); Effexor XR 75mg(depression); Pulmicort/Airomir (asthma)
~vitamins/minerals/supplements; Probiotics....(RenewLife Ultimate Flora Critical Care + Primadophilus Reuteri). @ bedtime
~various digestive enzymes as needed
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS" worth it !!!