Ask your doctor about 6MP, but don't let him start you at a high dosage. It takes about three months for it to "kick in" along with taking a low dose of prednisone. I started on it about seven years ago and did have a remission period (no symptoms of Ulcerative proctitis at all) of a few years, but it didn't keep me in remission. I have flares about once a year. I was hospitalized in May of 08 for ten days and that flare lasted until the first of Nov. I did enjoy a remission until this past May. I sometimes think my diet contributed to this last flare. We were vacationing and going to dinner with friends often. A high fat diet is NOT GOOD and I did eat steak a few times and pizza. These are foods I avoid eating when at home, so I should know better, so I am suffering for it now. I am not a candidate for Remicade as I was exposed to the TB virus back in the 60's and Remicade could reactive the TB.
I mentioned asking about the 6MP but you have to have a blood test called Prometheus prior to starting the 6MP to see if your system can metabolyze it properly. Why my GI doctor started me on it and didn't send me for the blood test until three months later will always be a mystery to me. I was on 50 mgm but he increased my dosage to 100 mgm because of my flare.....however, the 100 mgm sent my white blood cell count plummeting to 1.4, which means my immune system just about crashed. Now he took me off the drug completely for a few weeks to see if my white cell count will improve. If you do go on 6MP, make sure your doctor sends you for frequent CBC's to make sure your white count doesn't drop like mine did.
62 yr old granny. South Jersey
Diagnosed with ulcerative proctitis in 1998 in hospital
Hospitalized (2nd time) in May 2008
Meds as of June 09: Colazal (6 per day), 6MP (50 mgm), Probiotic (upped to 3 per day), Fish oil capsule, calcium, multivitamin, Cort enema nightly, Canasa in morning. Also taking Benicar and Toprol to control high blood pressure. Getting old is a b****.