VSL3 causing runny stools?? anyone else experience this??

New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

Regular Member

Date Joined Jun 2007
Total Posts : 49
   Posted 8/22/2009 6:50 AM (GMT -6)   
A few months ago I tried using VSL3...after a few weeks I developed very runny, soft, foul smelling stools. the symptoms i had were nothing like my usual UC flare symptoms, but much different. at first I didn't know what was going on...knowing that something was wrong, but also knowing that this wasn't my usual UC symptoms. even taking immodium every day didn't help. i went to the doctor, took stool tests, blood tests etc. and they found nothing wrong. then i stopped taking the VSL3 since this was the only change in my diet i had made in the last few weeks. I never thought to stop taking it before because I didn't think it was the cause of my problems. After about a week of not taking the VSL3, my symptoms stopped and I was fine. Not completely convinced it was the VSL3 causing the problem...after a couple months I started taking VSL3 again, and after a few weeks the same thing happened!! I stopped taking it, and after a week the symptoms again disappeared. I also again went to the dr. and had more stool and blood tests with no infection etc. I researched online and found that in rare cases VSL3 can cause some type of over colonization in the colon.
My question is... has anyone else experienced this before?? VSL3 is suppose to stop diarrhea, not cause it!!

thanks so much!!!!
30 yr old female, Cambridge Ma
Diagnosed with UC at age 14.
Colazel, Remicade ever 8 weeks, folic acid, multi vitamin, calcium, rowasa when needed

Been in remission for about 4 years since starting Remicade.

Veteran Member

Date Joined Dec 2007
Total Posts : 536
   Posted 8/22/2009 9:14 AM (GMT -6)   
I took VSL#3 for 2 and a half months and it did not help my D - perhaps it is better for constipation.
23 years of UC which started after quitting smoking. In and out of flares which are usually triggered by antibiotics. Latest issue is endless diarrhea without blood or mucous.


Elite Member

Date Joined Mar 2003
Total Posts : 10407
   Posted 8/22/2009 9:18 AM (GMT -6)   
I had increased cramping and gas when I tried it for 4 months.

Not all probiotics suit all people. Sometimes you have to experiment a bit before you find on that works for you.
 Ulcerative colitis forum co-moderator
Moderate to severe left-sided UC diagnosed 2001. Flared for 5 years, finally in remission with Remicade since March 2006. Colazal,  Remicade, Nature's Way Primadophilus Reuteri.
Avascular necrosis in both shoulders is  my "forever" gift from steroids.
Chronic joint/connective tissue/muscle pain; TKR 05/09 
"My life is an ongoing medical adventure"

Regular Member

Date Joined Dec 2008
Total Posts : 224
   Posted 8/23/2009 9:51 AM (GMT -6)   
You may be experiencing some variant of the herxheimer reaction resulting from a relatively large dose of probiotics. This apparently can cause a number of unpleasant things, including diarrhea.

Perhaps starting at a lower dose and gradually working your way up to the full dose will help. In any event, I wouldn't give up on probiotics just yet. It can take a while to see positive results - and as Judy mentioned - may take some experimentation to find what works best for you.
Diagnosed with UC in 1990.
Current Meds: Sulfasalazine & Folic Acid.
Supplements: fish oil, flax oil, glucosamine, CoQ10, fiber, aloe vera juice, probiotics.
Other: Raw Milk for breakfast. Currently exploring a raw milk fast one day/week.

New Topic Post Reply Printable Version
Forum Information
Currently it is Tuesday, September 25, 2018 12:05 PM (GMT -6)
There are a total of 3,006,467 posts in 329,342 threads.
View Active Threads

Who's Online
This forum has 161835 registered members. Please welcome our newest member, scattycatty.
273 Guest(s), 11 Registered Member(s) are currently online.  Details
bobmars, HeartsinPain, mattamx, xpeetzax, sebreg, Tredye, Admin, BillyBob@388, Sherrine, turtlepower, iPoop