Skin problems and discoloration on prednisone

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Regular Member

Date Joined Jul 2009
Total Posts : 37
   Posted 8/23/2009 10:02 PM (GMT -6)   
I've noticed for a few weeks now that my chest is always flushed. It looks like I got sunburn 3 days ago every day. And now the tops of my arms look flushed/purplish. I haven't gained weight, but I'm worried about getting stretch marks on my thighs because I think I see little striations. Maybe I'm just being paranoid though. I heard that it can make your skin thinner and I feel like I can see my veins a lot more prominently. It doesn't help that I'm kind of pale anyway I'm sure.
But I found 2 different small spots on my legs were I have these spider vein looking things. I don't know if maybe I hit myself or what. And I think I can see the hair follicles on my leg more even after shaving.
I'm almost 19 so the spider veins are not something that should be happening. My moon face started about 3 weeks ago and my face stays flushed longer when I wake up in the mornings.
I've been on the pred since December, 30mg with a slow taper down to 10mg. Started having problems off and on and then it got to the point that my doc put me up on 40mg at the end of June. No taper yet :-( I will probably start 6-MP or Remicade in a few weeks if I don't improve.
40mg pred
9 colazal (switched from 12 asacol about 5 weeks ago)
1 canasa at night (no improvement yet...10 days)
yaz for cramps (I think i'm going to stop it after my next cycle to see if that helps anything)
folic acid
vitamin a/d supplement
allign probiotics

Regular Member

Date Joined Jul 2009
Total Posts : 37
   Posted 8/26/2009 5:03 PM (GMT -6)   
Has anyone else had a problem with this?

Regular Member

Date Joined Jul 2009
Total Posts : 90
   Posted 8/26/2009 5:25 PM (GMT -6)   
Yeah. I'm always red. I look like I've been exercising or in the sun. Always flushed. I have gained weight on pred and definitely got stretch marks. First time I took it, after my son was born, I gained 80 lbs in 4 months. Can't avoid them that way. No one warned me about the weight gain. It was really depressing. I'm happy you haven't gained weight. You probably won't get stretch marks unless you have some type of rapid weight gain. Make sure you use lotion to help keep your skin elastic.

I've been on it since April this last time, and am ready to be off of it. I am trying to get Remicade started, too.

My face is so fat and round I want to rip it off. I haven't really notice spider veins as much. I do have some. I have noticed some in my face around my cheeks and chin. My complexion is really horrible and the last few times I have been on pred I have gotten really oily skin and blemishes.
33 year old female, one 13 year old son
diagnosed 1995 age 19 (was pregnant with son)
currently on
Imuran 200 mg
prednisone 20 mg
levsin 4 .125 mg a day
b complex
grape seed extract
flax oil
fish oil

Veteran Member

Date Joined Aug 2008
Total Posts : 5975
   Posted 8/26/2009 7:34 PM (GMT -6)   
      I get the flushing too.  Weird that I never gain weight while on prednisone.  I do get the moon face though.   I really watch my diet while flaring, therefore, no weight gain.  I eat salmon three times a week, tilapia at least once and chicken on the other days.  Since my blood sugar went up with this round of prednisone I watch my carbs and sugar intake.
     Be sure to take a calcium supplement while on prednisone.  I developed osteoporosis.
Diagnosed with ulcerative proctitis in 1998 in hospital
Hospitalized (2nd time) in May 2008 for ten days.
Remission Nov 08 thru May of 09.
Slowly coming out of flare.  Meds: Colazal (6 per day), prednisone 10 mgm and tapering weekly, Cort enema nightly, Canasa in morning, Benicar 20 mg for BP, flaxseed oil 3 x a day, fishoil 2 x a day, probiotic 3 x a day, calcium with D 1x a day and multivitamin.
Doctor had me on 100 mgm of 6MP which drastically lowered my white count.  Now off the 6MP pending results of repeat white count. UGH.

Darth Squiddious
Regular Member

Date Joined Aug 2009
Total Posts : 30
   Posted 8/26/2009 7:38 PM (GMT -6)   
I've got the fat face and a hellacious case of acne on my forehead and shoulders. 12 more weeks and I'll be off this stuff.
Officially Diagnosed with Ulcerative Colitis on 8/03/2009
Flared from April 2009 - August 2009
My cocktail that's worked since 8/19/2009
Lialda 2.4G daily
Prednisone 20mg x2 daily (tapering off)
Imuran 50mg x3 daily
Hydrocodone 5/500 as needed for pain
Nexium 40mg daily for heartburn

Regular Member

Date Joined Jul 2009
Total Posts : 321
   Posted 8/26/2009 7:55 PM (GMT -6)   
I got flushed alot when I was on the pred. Plus I got acne on my back...The side effects suck but most of them go away once your off it.
UC since 2002- remission for 6 years
recent flare 06/09
Currently on Colazal, multivitamin, probiotics, fish oil
just tapered off prednisone

Regular Member

Date Joined Jun 2007
Total Posts : 364
   Posted 8/27/2009 5:40 AM (GMT -6)   
My son doesn't really gain much weight on prednisone, but it makes his legs look like he has been attacked by a weed whacker with all the stretch marks from his ankles to his waist. Sometimes he even gets them near his armpits. I wish he would let me take a picture as it is unbelievable. It is because Pred thins the skin, not because of weight gain (at least in his case).

This time he was on it for a short time so it's looking like he'll not get the stretch marks - either that or there is not room for more :-(

He does have a bit of flushing, and had a breakout of small bumps/acne on his chest.

Hope you are able to get off of it soon.

Mom of Son 17 UC dx 07/02, Prednisone 2.5 mg, Lailda 2 am & 1 pm, Azasan 100mg, folic acid, L. Reuteri, Culturelle, Zyrtec, Iron, Vit/Min

Daughter 10 UC dx 08/07 Prednisone 2.5 mg, Colazal 750mg x 4, 6MP 12.5mg, Iron, Vit/Min., Culturelle

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