isn't that weird! I googled longterm outcomes in UC, & that was one of the results. I was able to read it fine- then, when I copied & pasted the web address you get the member log-in request! I'll try to cut & paste the text instead, just the first part.
Why Is Maintenance of Remission Therapy Necessary?
Ulcerative colitis is an idiopathic chronic inflammatory disease of the colon with clinical symptoms of rectal bleeding and diarrhea. Epidemiologic studies in patients with ulcerative colitis have reported that over 90% of patients have symptoms of active disease during the first year following diagnosis, and that in subsequent years, approximately 50% of patients will be in symptomatic remission in any given year, with the remainder of patients either having active disease or having undergone colectomy. If the window of observation is widened from 1 year to 5 years, then 25% of patients will have disease continuously in remission over a 5-year period, 18% of patients will have continuously active disease, and the remaining 57% of patients will alternate between symptomatic remission and relapse. Thus, without maintenance therapy, the majority of patients will experience symptomatic relapse over a 5-year period. In addition to clinical symptoms that patients experience with relapse, relapse also puts the patient at risk for colectomy and colorectal cancer. The 10-year cumulative risk for colectomy in patients with ulcerative colitis ranges from 9% to 21%. After 30 years from diagnosis, the cumulative probability of colorectal cancer in patients with ulcerative colitis approaches 15% to 20%, as compared with less than 5% for the general population. Chronic endoscopic and histologic inflammation is a risk factor for ulcerative colitis-associated colorectal. cancer. Maintenance therapy is indicated to prevent symptomatic and endoscopic relapse and to minimize the risk for colectomy and colorectal cancer.
well, that worked ok! the rest of the info was all about maint. therapy with various meds, but intersting too.
diagnosed with UC '02