prednisone alternative

New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

sgirl
Regular Member


Date Joined Jul 2009
Total Posts : 417
   Posted 8/25/2009 5:41 AM (GMT -6)   
So if there aren't enough topics on prednisone lately, here's another one.  :)
 
Prednisone has given me gestational diabetes among a whole other long list of things.  All the problems I'm having with this pregnancy basically stem from my prednisone.  Main concern right now is the GD.  Since it's steroid induced diabetes it is very difficult to treat during pregnancy and cannot be controlled through diet and excercise and I will most likely need insulin shots on a regular basis, maybe even every time I eat.
 
Is there something else other than prednisone that will help?  I've been on it since the end of Feb/beginning of March at a fairly constant 20mg (did taper off to 5 mg every other day but had to go back up to 20)  I'm on Lialda (4daily), probiotics, as well as prenatals and now I get to be on antibiotics for another prednisone side effect for at least the rest of my pregnancy. 
 
Thanks!
Diagnosed with UC in February 2009, has had an ongoing flare up since October 2008.
 
Medication: Lialda 4xdaily, 20 mg Prednisone, and 1 mg Robinul when needed. 
 
Pregnant with Miss Gummy Bean and due November 10th!


Darth Squiddious
Regular Member


Date Joined Aug 2009
Total Posts : 30
   Posted 8/25/2009 5:48 AM (GMT -6)   
Hey, my doctor just started me on Imuran last week and it's a lifesaver. Prednisone is an ugly drug. I honestly can't understand why they prescribe it to begin with or why they would have allowed you to take it while pregnant. Anyway, Imuran (I'm not sure about taking it while pregnant though) seems to be doing what it's supposed to. Nothing was getting better until I started on it, so I'm guessing that it's the cause of this last week being so good.
Diagnosed with Ulcerative Colitis on 8/03/2009
My cocktail that's worked since 8/19/2009
Centrum
Lialda 2.4G daily
Prednisone 20mg x2 daily (tapering off)
Imuran 50mg x3 daily


mindstyle
Regular Member


Date Joined Aug 2009
Total Posts : 62
   Posted 8/25/2009 9:54 AM (GMT -6)   
My 2 cents.

We are talking about 2 different drugs.
Prednisolone is a cortisone and its best to control acute flare of UC through its anti-inflammatory response.
Imuran, if I am right, contains Azathioprine and is immunosuppresant. The mode of action of both the drugs is different. Prednisolone controls your acute flare up and then Azathioprine should control your immune reaction in long terms.

Those who are on immunosuppresants should be very careful, they tend to get infections quite fast.

sgirl
Regular Member


Date Joined Jul 2009
Total Posts : 417
   Posted 8/25/2009 10:23 AM (GMT -6)   
Thanks guys! That is some good information for me :)

Unfortunately Imuran is considered a cat D drug during pregnancy according to my dr, I believe some places consider it a cat C. Either way it's not good during pregnancy, otherwise that is what I would be on instead of lialda and prednisone. After delivery that's what we're planning on switching to.

Pred has suppressed my immune system, has caused my GD making my sugars higher and undigested, which then has fed numerous UTI's of which my body can't fight off. It's a vicious cycle.

I hate prednisone... :(
Diagnosed with UC in February 2009, has had an ongoing flare up since October 2008.
 
Medication: Lialda 4xdaily, 20 mg Prednisone, and 1 mg Robinul when needed. 
 
Pregnant with Miss Gummy Bean and due November 10th!


quincy
Elite Member


Date Joined May 2003
Total Posts : 30999
   Posted 8/25/2009 3:02 PM (GMT -6)   
uh...rectal meds? curious why has that not been an option?  request them....they can work very well...
 
Why are you on Robinul?  is this for decreasing diarrhea?
 
q


*Heather* Status: ...Asacol 3 twice daily; Salofalk enemas every 3rd night
~diagnosed January 1989 UC (proctosigmoiditis)
~UC meds: Asacol (3 @ 2x daily); Salofalk enemas nightly for flares & taper to maintenance 
~Bentylol (dicyclomine) 20mg as needed; Ranitidine (reflux);  Effexor XR 75mg(depression);  Pulmicort/Airomir (asthma) 
~vitamins/minerals/supplementsProbiotics....(RenewLife Ultimate Flora Critical Care + Primadophilus Reuteri). @ bedtime
~various digestive enzymes as needed
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS"  worth it !!!
 


Darth Squiddious
Regular Member


Date Joined Aug 2009
Total Posts : 30
   Posted 8/25/2009 5:35 PM (GMT -6)   
mindstyle said...

Those who are on immunosuppresants should be very careful, they tend to get infections quite fast.


Thank you for the heads up.
Officially Diagnosed with Ulcerative Colitis on 8/03/2009
Flared from April 2009 - August 2009
My cocktail that's worked since 8/19/2009
Centrum
Lialda 2.4G daily
Prednisone 20mg x2 daily (tapering off)
Imuran 50mg x3 daily
Hydrocodone 5/500 as needed for pain
Nexium 40mg daily for heartburn


sirenshooter
Veteran Member


Date Joined Jun 2009
Total Posts : 2012
   Posted 8/25/2009 10:18 PM (GMT -6)   
Darth Squiddious said...
mindstyle said...

Those who are on immunosuppresants should be very careful, they tend to get infections quite fast.


Thank you for the heads up.

 
Darth, I'm on 125mg (almost as much as you) and I don't get sick more than anyone else. I take vitamin C when there are sickies around or if a cold catches me and I do fine. =)
 
Also, I'm wondering why you take it three times a day instead of one? That seems weird. Seeing as how long it takes to kick in and also how it takes a while to leave the system, I don't see the benefit. It would be easier to take it all at once. Unless it makes you nauseous? Just curious
19yr old female diagnosed with UC (pancolitis) in 2005 at age 15
125mg Azathioprine 1xday / 1 Mesalamine enema every night /
2000mg Fish Oil 1xday / 500mg Turmeric 3xday /
450mg Boswellia 2xday / 400IU Vitamin E 1xday
Arthritis in both knees
Also: asthma, acid reflux, and Reynaud's Syndrome


Darth Squiddious
Regular Member


Date Joined Aug 2009
Total Posts : 30
   Posted 8/25/2009 10:41 PM (GMT -6)   
ElephantPipe said...

Also, I'm wondering why you take it three times a day instead of one? That seems weird. Seeing as how long it takes to kick in and also how it takes a while to leave the system, I don't see the benefit. It would be easier to take it all at once. Unless it makes you nauseous? Just curious


6am, 2pm, 10pm.

I don't know why, that's just how the doc's got it prescribed. He's been an award winning GI for 35 years and is one of the best in DFW (I'm actually really lucky considering the military normally sends you to whatever random doctor pops up in the computer), so I trust it. My only guess is it might be because I'm just starting the prednisone taper.

So far, I've experienced no side effects from it. Maybe a little more gas than normal, but my UC finally went into remission and it happened 3 days after I started the Imuran. I'm down to 1-2 trips to the commode a day and the results have been solid since Saturday. I'm really hyped.
Officially Diagnosed with Ulcerative Colitis on 8/03/2009
Flared from April 2009 - August 2009
My cocktail that's worked since 8/19/2009
Centrum
Lialda 2.4G daily
Prednisone 20mg x2 daily (tapering off)
Imuran 50mg x3 daily
Hydrocodone 5/500 as needed for pain
Nexium 40mg daily for heartburn


sirenshooter
Veteran Member


Date Joined Jun 2009
Total Posts : 2012
   Posted 8/26/2009 6:12 PM (GMT -6)   
Oh well that's cool dude. I don't get any side-effects either. Woo!
19yr old female diagnosed with UC (pancolitis) in 2005 at age 15
125mg Azathioprine 1xday / 1 Mesalamine enema every night /
2000mg Fish Oil 1xday / 500mg Turmeric 3xday /
450mg Boswellia 2xday / 400IU Vitamin E 1xday
Arthritis in both knees
Also: asthma, acid reflux, and Reynaud's Syndrome


Dr-A
Veteran Member


Date Joined Jul 2006
Total Posts : 2105
   Posted 8/26/2009 7:34 PM (GMT -6)   
quincy said...
uh...rectal meds? curious why has that not been an option? request them....they can work very well...


Why are you on Robinul? is this for decreasing diarrhea?



q


I second, third, and fourth this question. ?? Have you already done them?
Proctitis DX 1999, Pancolitis DX 2008
Golimumab study (100mg every 4 weeks)
L-Glutamine 5000 mg + 600 mg pyridoxal alpha-ketoglutarate
Probiotis/VitD3 5000IU+Ca/1000mg DHA


jujub
Elite Member


Date Joined Mar 2003
Total Posts : 10407
   Posted 8/26/2009 7:41 PM (GMT -6)   
Darth, Imuran takes one to three months (sometimes up to six months) to build to an effective level in your body. Your improvement is likely related to the Lialda or Prednisone. Hopefully the Imuran will help to maintain it as it kicks in.
Judy
 Ulcerative colitis forum co-moderator
 
Moderate to severe left-sided UC diagnosed 2001. Flared for 5 years, finally in remission with Remicade since March 2006. Colazal,  Remicade, Nature's Way Primadophilus Reuteri.
Avascular necrosis in both shoulders is  my "forever" gift from steroids.
Chronic joint/connective tissue/muscle pain; TKR 05/09 
"My life is an ongoing medical adventure"
 

New Topic Post Reply Printable Version
Forum Information
Currently it is Monday, September 24, 2018 4:51 AM (GMT -6)
There are a total of 3,005,994 posts in 329,291 threads.
View Active Threads


Who's Online
This forum has 161818 registered members. Please welcome our newest member, demonsss.
211 Guest(s), 1 Registered Member(s) are currently online.  Details
M. Lowe